Varaico: Literature-Extracted Genetic Variants

Gene:UGT1A1
Variant:p.E417K
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UGT1A1

NM_000463.3:p.E417K

Associated Papers

Comprehensive analysis of important pharmacogenes in Koreans using the DMET™ platform.

Kim B et al.

Translational and Clinical Pharmacology, 2021

34621706 (PubMed )
Supplement: tcp-29-135-s001.xls › tcp-29-135-s001

ABCC5 and ABCG1 polymorphisms predict irinotecan-induced severe toxicity in metastatic colorectal cancer patients.

Chen S et al.

Pharmacogenetics and Genomics, 2015

The Affymetrix DMET Plus platform reveals unique distribution of ADME-related variants in ethnic Arabs.

Wakil SM et al.

Disease Markers, 2015

25802476 (PubMed )
Supplement: 542543.f1.xlsx › DMET_Suppl_data

Pharmacogenetics of antiretroviral therapy.

Barreiro P et al.

Expert Opinion on Drug Metabolism & Toxicology, 2014

Potentially functional SNPs (pfSNPs) as novel genomic predictors of 5-FU response in metastatic colorectal cancer patients.

Wang J et al.

Plos One, 2014

25372392 (PubMed )
Supplement: pone.0111694.s006.pdf

The impact of pharmacogenetics of metabolic enzymes and transporters on the pharmacokinetics of telmisartan in healthy volunteers.

Yamada A et al.

Pharmacogenetics and Genomics, 2011

Analysis of pharmacogenetic traits in two distinct South African populations.

Ikediobi O et al.

Human Genomics, 2011

Association of ATP-binding cassette, sub-family C, number 2 (ABCC2) genotype with pharmacokinetics of irinotecan in Japanese patients with metastatic colorectal cancer treated with irinotecan plus infusional 5-fluorouracil/leucovorin (FOLFIRI).

Fujita K et al.

Biological & Pharmaceutical Bulletin, 2008

Multidrug resistance protein 2 genetic polymorphisms influence mycophenolic acid exposure in renal allograft recipients.

Naesens M et al.

Transplantation, 2006

Pharmacogenetic screening for polymorphisms in drug-metabolizing enzymes and drug transporters in a Dutch population.

Bosch TM et al.

Molecular Diagnosis & Therapy, 2006

Predicting drug response and toxicity based on gene polymorphisms.

Robert J et al.

Critical Reviews in Oncology/hematology, 2005

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