Varaico: Literature-Extracted Genetic Variants

Gene:UGT1A10
Variant:p.M59I
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UGT1A10

NM_019075.4:p.M59I

Associated Papers

Dolutegravir metabolism: impact of genetic variations on uridine diphosphate glucuronosyltransferase subfamilies.

Tagawa K et al.

Xenobiotica; the Fate of Foreign Compounds in Biological Systems, 2025

APF2: an improved ensemble method for pharmacogenomic variant effect prediction.

Zhou Y et al.

The Pharmacogenomics Journal, 2024

38802404 (PubMed )
Supplement: 41397_2024_338_MOESM2_ESM.xlsx › Sheet1

An optimized prediction framework to assess the functional impact of pharmacogenetic variants.

Zhou Y et al.

The Pharmacogenomics Journal, 2019

30206299 (PubMed )
Supplement: 41397_2018_44_MOESM5_ESM.xlsx › Sheet1

Influence of drug transporters and UGT polymorphisms on pharmacokinetics of phenolic glucuronide metabolite of mycophenolic acid in Japanese renal transplant recipients.

Miura M et al.

Therapeutic Drug Monitoring, 2008

Update on tools for evaluation of uridine diphosphoglucuronosyltransferase polymorphisms.

Argikar UA et al.

Expert Opinion on Drug Metabolism & Toxicology, 2008

Variability and function of family 1 uridine-5'-diphosphate glucuronosyltransferases (UGT1A).

Strassburg CP et al.

Critical Reviews in Clinical Laboratory Sciences, 2008

Uridine diphosphoglucuronosyltransferase pharmacogenetics and cancer.

Nagar S et al.

Oncogene, 2006

Amino acid residue ILE211 is essential for the enzymatic activity of human UDP-glucuronosyltransferase 1A10 (UGT1A10).

Martineau I et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2004

Functional characterization of wild-type and variant (T202I and M59I) human UDP-glucuronosyltransferase 1A10.

Jinno H et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2003

Three novel single nucleotide polymorphisms in UGT1A10.

Saeki M et al.

Drug Metabolism and Pharmacokinetics, 2002

Haplotype structures of the UGT1A gene complex in a Japanese population.

Saeki M et al.

The Pharmacogenomics Journal, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."