Varaico: Literature-Extracted Genetic Variants

Gene:UGT1A3
Variant:p.R45W
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UGT1A3

NM_019093.4:p.R45W

Associated Papers

The pharmacogenomic landscape in the Chinese: An analytics of pharmacogenetic variants in 206,640 individuals.

Wang LY et al.

Innovation (cambridge (mass.)), 2025

39991480 (PubMed )
Supplement: mmc5.xlsx › Sheet1

Identification of potentially deleterious mutations in gastric cancer using patient-derived xenograft models.

Kong L et al.

Frontiers in Genetics, 2025

Population-specific putative causal variants shape quantitative traits.

Koyama S et al.

Nature Genetics, 2024

39363016 (PubMed )
Supplement: 41588_2024_1913_MOESM3_ESM.xlsx › ST8_Missense_PPI___0.1

Genomic characteristics and immune landscape of super multiple primary lung cancer.

Yang Z et al.

Ebiomedicine, 2024

38364701 (PubMed )
Supplement: mmc2.xlsx › all_212.somatic.igv_recheck.mut

Assessing the contribution of UGT isoforms on raltegravir drug disposition through PBPK modeling.

Moreira FD et al.

European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences, 2022

Clinicopathological characteristics and molecular abnormalities of primary grade 2 neuroendocrine tumors of the cervix.

Zhu R et al.

Diagnostic Pathology, 2019

Pharmacogenetic study of deferasirox, an iron chelating agent.

Lee JW et al.

Plos One, 2013

Prediction of deleterious non-synonymous single-nucleotide polymorphisms of human uridine diphosphate glucuronosyltransferase genes.

Di YM et al.

The Aaps Journal, 2009

Do single nucleotide polymorphisms in xenobiotic metabolizing genes determine breast cancer susceptibility and treatment outcomes?

Singh V et al.

Cancer Investigation, 2008

Update on tools for evaluation of uridine diphosphoglucuronosyltransferase polymorphisms.

Argikar UA et al.

Expert Opinion on Drug Metabolism & Toxicology, 2008

Genetic variations and haplotypes of UDP-glucuronosyltransferase 1A locus in a Korean population.

Yea SS et al.

Therapeutic Drug Monitoring, 2008

Critical roles of residues 36 and 40 in the phenol and tertiary amine aglycone substrate selectivities of UDP-glucuronosyltransferases 1A3 and 1A4.

Kubota T et al.

Molecular Pharmacology, 2007

A pharmacogenomics study of the human estrogen glucuronosyltransferase UGT1A3.

Caillier B et al.

Pharmacogenetics and Genomics, 2007

Genetic variants of human UGT1A3: functional characterization and frequency distribution in a Chinese Han population.

Chen Y et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2006

Six novel UDP-glucuronosyltransferase (UGT1A3) polymorphisms with varying activity.

Iwai M et al.

Journal of Human Genetics, 2004

Haplotype structures of the UGT1A gene complex in a Japanese population.

Saeki M et al.

The Pharmacogenomics Journal, 0

Novel polymorphisms associated with hyperalphalipoproteinemia and apparent cardioprotection.

Oates CP et al.

Journal of Clinical Lipidology, 0

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