Associated Papers
Identification of Genetic Variants Associated with Pravastatin and Pitavastatin Pharmacokinetics.
Mykkänen AJH et al.
Clinical Pharmacology and Therapeutics, 2025
A Common UDP-Glucuronosyltransferase (UGT)1A Haplotype Is Associated With Accelerated Aging in Humanized Transgenic Mice.
Langhans B et al.
Oxidative Medicine and Cellular Longevity, 2025
Mapping and annotating genomic loci to prioritize genes and implicate distinct polygenic adaptations for skin color.
Kim B et al.
Nature Communications, 2024
Genome-Wide Association Study of Atorvastatin Pharmacokinetics: Associations With SLCO1B1, UGT1A3, and LPP.
Mykkänen AJH et al.
Clinical Pharmacology and Therapeutics, 2024
Evolutionary history of adenomas to colorectal cancer in FAP families.
Yang C et al.
Frontiers in Genetics, 2024
Somatic mutations reveal hyperactive Notch signaling and racial disparities in prurigo nodularis.
Rajeh A et al.
Medrxiv : the Preprint Server for Health Sciences, 2023
Genetic Variant ABCC1 rs45511401 Is Associated with Increased Response to Statins in Patients with Familial Hypercholesterolemia.
Dagli-Hernandez C et al.
Pharmaceutics, 2022
Pharmacokinetics and safety of a novel influenza treatment (baloxavir marboxil) in Korean subjects compared with Japanese subjects.
Kim Y et al.
Clinical and Translational Science, 2022
Prioritization of candidate genes for a South African family with Parkinson's disease using in-silico tools.
Sebate B et al.
Plos One, 2021
UGT1A3 and Sex Are Major Determinants of Telmisartan Pharmacokinetics-A Comprehensive Pharmacogenomic Study.
Hirvensalo P et al.
Clinical Pharmacology and Therapeutics, 2020
Comprehensive Pharmacogenomic Study Reveals an Important Role of UGT1A3 in Montelukast Pharmacokinetics.
Hirvensalo P et al.
Clinical Pharmacology and Therapeutics, 2018
The UGT1 locus is a determinant of prostate cancer recurrence after prostatectomy.
Laverdière I et al.
Endocrine-related Cancer, 2015
Pharmacogenetic study of deferasirox, an iron chelating agent.
Lee JW et al.
Plos One, 2013
Associations between polymorphisms in glucuronidation and sulfation enzymes and sex steroid concentrations in premenopausal women in the United States.
Yong M et al.
The Journal of Steroid Biochemistry and Molecular Biology, 2011
Genetic polymorphism in metabolism and host defense enzymes: implications for human health risk assessment.
Ginsberg G et al.
Critical Reviews in Toxicology, 2010
Associations between polymorphisms in glucuronidation and sulfation enzymes and mammographic breast density in premenopausal women in the United States.
Yong M et al.
Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2010
UDP-glucuronosyltransferase (UGT) polymorphisms affect atorvastatin lactonization in vitro and in vivo.
Riedmaier S et al.
Clinical Pharmacology and Therapeutics, 2010
Analysis of inherited genetic variations at the UGT1 locus in the French-Canadian population.
Ménard V et al.
Human Mutation, 2009
Do single nucleotide polymorphisms in xenobiotic metabolizing genes determine breast cancer susceptibility and treatment outcomes?
Singh V et al.
Cancer Investigation, 2008
Aryl hydrocarbon receptor-mediated regulation of the human estrogen and bile acid UDP-glucuronosyltransferase 1A3 gene.
Lankisch TO et al.
Archives of Toxicology, 2008
Family 1 uridine-5'-diphosphate glucuronosyltransferases (UGT1A): from Gilbert's syndrome to genetic organization and variability.
Strassburg CP et al.
Archives of Toxicology, 2008
Update on tools for evaluation of uridine diphosphoglucuronosyltransferase polymorphisms.
Argikar UA et al.
Expert Opinion on Drug Metabolism & Toxicology, 2008
Genetic variations and haplotypes of UDP-glucuronosyltransferase 1A locus in a Korean population.
Yea SS et al.
Therapeutic Drug Monitoring, 2008
Variability and function of family 1 uridine-5'-diphosphate glucuronosyltransferases (UGT1A).
Strassburg CP et al.
Critical Reviews in Clinical Laboratory Sciences, 2008
Critical roles of residues 36 and 40 in the phenol and tertiary amine aglycone substrate selectivities of UDP-glucuronosyltransferases 1A3 and 1A4.
Kubota T et al.
Molecular Pharmacology, 2007
A pharmacogenomics study of the human estrogen glucuronosyltransferase UGT1A3.
Caillier B et al.
Pharmacogenetics and Genomics, 2007
Genetic variants of human UGT1A3: functional characterization and frequency distribution in a Chinese Han population.
Chen Y et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2006
Genetic variability, haplotypes, and htSNPs for exons 1 at the human UGT1A locus.
Thomas SS et al.
Human Mutation, 2006
Variation of hepatic glucuronidation: Novel functional polymorphisms of the UDP-glucuronosyltransferase UGT1A4.
Ehmer U et al.
Hepatology (baltimore, Md.), 2004
Six novel UDP-glucuronosyltransferase (UGT1A3) polymorphisms with varying activity.
Iwai M et al.
Journal of Human Genetics, 2004
Comparative genomics analysis of human sequence variation in the UGT1A gene cluster.
Maitland ML et al.
The Pharmacogenomics Journal, 0
Haplotype structures of the UGT1A gene complex in a Japanese population.
Saeki M et al.
The Pharmacogenomics Journal, 0