Varaico: Literature-Extracted Genetic Variants

Gene:UGT1A3
Variant:p.M270V
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UGT1A3

NM_019093.4:p.M270V

Associated Papers

Identification of Genetic Variants Associated with Pravastatin and Pitavastatin Pharmacokinetics.

Mykkänen AJH et al.

Clinical Pharmacology and Therapeutics, 2025

Genome-Wide Association Study of Atorvastatin Pharmacokinetics: Associations With SLCO1B1, UGT1A3, and LPP.

Mykkänen AJH et al.

Clinical Pharmacology and Therapeutics, 2024

The atorvastatin metabolite pattern in muscle tissue and blood plasma is associated with statin muscle side effects in patients with coronary heart disease; An exploratory case-control study.

Lauritzen T et al.

Atherosclerosis Plus, 2024

When the same treatment has different response: The role of pharmacogenomics in statin therapy.

Zheng E et al.

Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie, 2024

Genetic Variant ABCC1 rs45511401 Is Associated with Increased Response to Statins in Patients with Familial Hypercholesterolemia.

Dagli-Hernandez C et al.

Pharmaceutics, 2022

UGT1A3 and Sex Are Major Determinants of Telmisartan Pharmacokinetics-A Comprehensive Pharmacogenomic Study.

Hirvensalo P et al.

Clinical Pharmacology and Therapeutics, 2020

Comprehensive Pharmacogenomic Study Reveals an Important Role of UGT1A3 in Montelukast Pharmacokinetics.

Hirvensalo P et al.

Clinical Pharmacology and Therapeutics, 2018

28940478 (PubMed )
Supplement: CPT-104-158-s005.pdf

Pharmacogenetic Variation in Over 100 Genes in Patients Receiving Acenocumarol.

Gonzalez-Covarrubias V et al.

Frontiers in Pharmacology, 2017

29218011 (PubMed )
Supplement: Table1.XLSX › ST1_targetgenes

The New Immortalized Uroepithelial Cell Line HBLAK Contains Defined Genetic Aberrations Typical of Early Stage Urothelial Tumors.

Hoffmann MJ et al.

Bladder Cancer (amsterdam, Netherlands), 2016

28035326 (PubMed )
Supplement: blc-2-blc160065-s001.xlsx › 2_HBLAK_relevant_SNPs

The UGT1A3*2 polymorphism affects atorvastatin lactonization and lipid-lowering effect in healthy volunteers.

Cho SK et al.

Pharmacogenetics and Genomics, 2012

UDP-glucuronosyltransferase (UGT) polymorphisms affect atorvastatin lactonization in vitro and in vivo.

Riedmaier S et al.

Clinical Pharmacology and Therapeutics, 2010

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."