Associated Papers
No association between non-bullous skin reactions from lamotrigine and heterozygosity of UGT1A4 genetic variants *2(P24T) or *3(L48V) in Norwegian patients.
Shirzadi M et al.
Seizure, 2017
Frequencies of UGT1A4*2 (P24T) and *3 (L48V) and their effects on serum concentrations of lamotrigine.
Reimers A et al.
European Journal of Drug Metabolism and Pharmacokinetics, 2016
Identification of aspartic acid and histidine residues mediating the reaction mechanism and the substrate specificity of the human UDP-glucuronosyltransferases 1A.
Li D et al.
The Journal of Biological Chemistry, 2007
Critical roles of residues 36 and 40 in the phenol and tertiary amine aglycone substrate selectivities of UDP-glucuronosyltransferases 1A3 and 1A4.
Kubota T et al.
Molecular Pharmacology, 2007
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