Associated Papers
Hepatic Cytochrome P450 Enzymatic System Interaction With Platelet Function and Cardiovascular Outcomes-Pharmacogenomic Impact on Inter-Organ Communication.
Figueiral M et al.
Comprehensive Physiology, 2025
A Common UDP-Glucuronosyltransferase (UGT)1A Haplotype Is Associated With Accelerated Aging in Humanized Transgenic Mice.
Langhans B et al.
Oxidative Medicine and Cellular Longevity, 2025
Genomic characteristics and immune landscape of super multiple primary lung cancer.
Yang Z et al.
Ebiomedicine, 2024
Novel NARS2 variants in a patient with early-onset status epilepticus: case study and literature review.
Yang N et al.
Bmc Pediatrics, 2024
Effects of common genetic variants of human uridine diphosphate glucuronosyltransferase subfamilies on irinotecan glucuronidation.
Tagawa K et al.
Toxicology Mechanisms and Methods, 2023
Chemotherapy-related hyperbilirubinemia in pediatric acute lymphoblastic leukemia: a genome-wide association study from the AIEOP-BFM ALL study group.
Junk SV et al.
Journal of Experimental & Clinical Cancer Research : Cr, 2023
Molecular monitoring of patient response to painkiller drugs.
Ayuso P et al.
Expert Review of Molecular Diagnostics, 2022
Common UGT1A6 Variant Alleles Determine Acetaminophen Pharmacokinetics in Man.
Cerezo-Arias MLO et al.
Journal of Personalized Medicine, 2022
Pharmacogenomic study of anthracycline-induced cardiotoxicity in Mexican pediatric patients.
Vargas-Neri JL et al.
Pharmacogenomics, 2022
Genetic polymorphisms associated with upper gastrointestinal bleeding: a systematic review.
Forgerini M et al.
The Pharmacogenomics Journal, 2021
Prioritization of candidate genes for a South African family with Parkinson's disease using in-silico tools.
Sebate B et al.
Plos One, 2021
PAIRUP-MS: Pathway analysis and imputation to relate unknowns in profiles from mass spectrometry-based metabolite data.
Hsu YH et al.
Plos Computational Biology, 2019
Interaction between polymorphisms in aspirin metabolic pathways, regular aspirin use and colorectal cancer risk: A case-control study in unselected white European populations.
Sheth H et al.
Plos One, 2018
Genetic predisposition to lung cancer: comprehensive literature integration, meta-analysis, and multiple evidence assessment of candidate-gene association studies.
Wang J et al.
Scientific Reports, 2017
Candidate gene association studies and risk of Hodgkin lymphoma: a systematic review and meta-analysis.
Sud A et al.
Hematological Oncology, 2017
Effects of UGT1A9 genetic polymorphisms on monohydroxylated derivative of oxcarbazepine concentrations and oxcarbazepine monotherapeutic efficacy in Chinese patients with epilepsy.
Lu Y et al.
European Journal of Clinical Pharmacology, 2017
Pharmacogenetic Variation in Over 100 Genes in Patients Receiving Acenocumarol.
Gonzalez-Covarrubias V et al.
Frontiers in Pharmacology, 2017
Genetic polymorphisms in UDP-glucuronosyltransferase 1A6 and 1A7 and the risk for benign Warthin's tumors of the parotid gland.
Lacko M et al.
Head & Neck, 2016
Genetic polymorphisms of human UDP-glucuronosyltransferase (UGT) genes and cancer risk.
Hu DG et al.
Drug Metabolism Reviews, 2016
Tissue-specific patterns of gene expression in the epithelium and stroma of normal colon in healthy individuals in an aspirin intervention trial.
Thomas SS et al.
Genomics Data, 2015
Exome-Wide Association Study Identifies New Low-Frequency and Rare UGT1A1 Coding Variants and UGT1A6 Coding Variants Influencing Serum Bilirubin in Elderly Subjects: A Strobe Compliant Article.
Oussalah A et al.
Medicine, 2015
Genetic variation in UGT genes modify the associations of NSAIDs with risk of colorectal cancer: colon cancer family registry.
Scherer D et al.
Genes, Chromosomes & Cancer, 2014
The effect of UGT1A and UGT2B polymorphisms on colorectal cancer risk: haplotype associations and gene–environment interactions.
Angstadt AY et al.
Genes, Chromosomes & Cancer, 2014
Molecular genetic mechanisms of chronic urticaria.
Losol P et al.
Allergy, Asthma & Immunology Research, 2014
Three most common nonsynonymous UGT1A6*2 polymorphisms (Thr181Ala, Arg184Ser and Ser7Ala) and therapeutic response to deferiprone in β-thalassemia major patients.
Dadheech S et al.
Gene, 2013
The effect of uridine diphosphate glucuronosyltransferase (UGT)1A6 genetic polymorphism on valproic acid pharmacokinetics in Indian patients with epilepsy: a pharmacogenetic approach.
Munisamy M et al.
Molecular Diagnosis & Therapy, 2013
Combined effect of genetic polymorphisms in phase I and II biotransformation enzymes on head and neck cancer risk.
Lacko M et al.
Head & Neck, 2013
Effect of common single-nucleotide polymorphisms in acetylsalicylic acid metabolic pathway genes on platelet reactivity in patients with diabetes.
Postula M et al.
Medical Science Monitor : International Medical Journal of Experimental and Clinical Research, 2013
The UDP-glucuronosyltransferase (UGT) 1A polymorphism c.2042C>G (rs8330) is associated with increased human liver acetaminophen glucuronidation, increased UGT1A exon 5a/5b splice variant mRNA ratio, and decreased risk of unintentional acetaminophen-induced acute liver failure.
Court MH et al.
The Journal of Pharmacology and Experimental Therapeutics, 2013
Refining the UGT1A haplotype associated with irinotecan-induced hematological toxicity in metastatic colorectal cancer patients treated with 5-fluorouracil/irinotecan-based regimens.
Lévesque E et al.
The Journal of Pharmacology and Experimental Therapeutics, 2013
The effect of genetic polymorphisms in UGT2B15 on the pharmacokinetic profile of sipoglitazar, a novel anti-diabetic agent.
Stringer F et al.
European Journal of Clinical Pharmacology, 2013
Clinical effectiveness of rivastigmine monotherapy and combination therapy in Alzheimer's patients.
Sonali N et al.
Cns Neuroscience & Therapeutics, 2013
Genetic association between obstructive bronchitis and enzymes of oxidative stress.
Bauer M et al.
Metabolism: Clinical and Experimental, 2012
Polymorphisms in carcinogen metabolism enzymes, fish intake, and risk of prostate cancer.
Catsburg C et al.
Carcinogenesis, 2012
Gilbert syndrome redefined: a complex genetic haplotype influences the regulation of glucuronidation.
Ehmer U et al.
Hepatology (baltimore, Md.), 2012
High enzyme activity UGT1A1 or low activity UGT1A8 and UGT2B4 genotypes increase esophageal cancer risk.
Dura P et al.
International Journal of Oncology, 2012
Mapping of the UGT1A locus identifies an uncommon coding variant that affects mRNA expression and protects from bladder cancer.
Tang W et al.
Human Molecular Genetics, 2012
The influence of UGT1A6 variants and aspirin use in a randomized trial of celecoxib for prevention of colorectal adenoma.
Chan AT et al.
Cancer Prevention Research (philadelphia, Pa.), 2012
Genetic variations and haplotype diversity of the UGT1 gene cluster in the Chinese population.
Yang J et al.
Plos One, 2012
Association between polymorphisms in UDP-glucuronosyltransferase 1A6 and 1A7 and colorectal cancer risk.
Osawa K et al.
Asian Pacific Journal of Cancer Prevention : Apjcp, 2012
UGT1A6 polymorphisms modulated lung cancer risk in a Chinese population.
Kua LF et al.
Plos One, 2012
Polymorphisms of Aspirin-Metabolizing Enzymes CYP2C9, NAT2 and UGT1A6 in Aspirin-Intolerant Urticaria.
Palikhe NS et al.
Allergy, Asthma & Immunology Research, 2011
UGT1A6 and UGT2B15 polymorphisms and acetaminophen conjugation in response to a randomized, controlled diet of select fruits and vegetables.
Navarro SL et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2011
Associations between polymorphisms in glucuronidation and sulfation enzymes and sex steroid concentrations in premenopausal women in the United States.
Yong M et al.
The Journal of Steroid Biochemistry and Molecular Biology, 2011
Genetic polymorphism in metabolism and host defense enzymes: implications for human health risk assessment.
Ginsberg G et al.
Critical Reviews in Toxicology, 2010
Aspirin-induced peptic ulcer and genetic polymorphisms.
Shiotani A et al.
Journal of Gastroenterology and Hepatology, 2010
Uridine 5'-diphospho-glucuronosyltransferase genetic polymorphisms and response to cancer chemotherapy.
Ramírez J et al.
Future Oncology (london, England), 2010
Interindividual variability in hepatic drug glucuronidation: studies into the role of age, sex, enzyme inducers, and genetic polymorphism using the human liver bank as a model system.
Court MH
Drug Metabolism Reviews, 2010