Varaico: Literature-Extracted Genetic Variants

Gene:UGT1A8
Variant:p.H53N
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UGT1A8

NM_019076.5:p.H53N

Associated Papers

In Vitro Study on Influences of UGT1A8 Gene Polymorphisms on Mycophenolate Mofetil Metabolism.

Zhou Z et al.

Experimental and Clinical Transplantation : Official Journal of the Middle East Society for Organ Transplantation, 2018

Mycophenolic acid AUC in Thai kidney transplant recipients receiving low dose mycophenolate and its association with UGT2B7 polymorphisms.

Pithukpakorn M et al.

Pharmacogenomics and Personalized Medicine, 2014

Prediction of deleterious non-synonymous single-nucleotide polymorphisms of human uridine diphosphate glucuronosyltransferase genes.

Di YM et al.

The Aaps Journal, 2009

The impact of UGT1A8, UGT1A9, and UGT2B7 genetic polymorphisms on the pharmacokinetic profile of mycophenolic acid after a single oral dose in healthy volunteers.

Lévesque E et al.

Clinical Pharmacology and Therapeutics, 2007

Influence of nonsynonymous polymorphisms of UGT1A8 and UGT2B7 metabolizing enzymes on the formation of phenolic and acyl glucuronides of mycophenolic acid.

Bernard O et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2006

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."