Associated Papers
Development and Verification of Virtual Population Models for Predicting Drug Pharmacokinetics in Ethnic North American Populations.
Ezuruike U et al.
Cpt: Pharmacometrics & Systems Pharmacology, 2025
Contrastive sequence signatures between the both sides of a recombination spot reveal an adaptation at PPARD locus from standing variation for pleiotropy since out-of-Africa dispersal.
Shou W et al.
Bmc Genomics, 2025
Genetic variants in patients with multiple arterial aneurysms.
Körfer D et al.
Langenbeck's Archives of Surgery, 2024
ATR represents a therapeutic vulnerability in clear cell renal cell carcinoma.
Seidel P et al.
Jci Insight, 2022
Sensitization of Patient-Derived Colorectal Cancer Organoids to Photon and Proton Radiation by Targeting DNA Damage Response Mechanisms.
Pape K et al.
Cancers, 2022
Whole-exome sequencing identifies somatic mutations and intratumor heterogeneity in inflammatory breast cancer.
Luo R et al.
Npj Breast Cancer, 2021
Implication of UGT2B15 Genotype Polymorphism on Postoperative Anxiety Levels in Patients Receiving Lorazepam Premedication.
Mijderwijk H et al.
Anesthesia and Analgesia, 2016
Classical and Non-Classical Roles for Pre-Receptor Control of DHT Metabolism in Prostate Cancer Progression.
Zhang A et al.
Hormones & Cancer, 2016
Genetic polymorphisms of human UDP-glucuronosyltransferase (UGT) genes and cancer risk.
Hu DG et al.
Drug Metabolism Reviews, 2016
The eSNV-detect: a computational system to identify expressed single nucleotide variants from transcriptome sequencing data.
Tang X et al.
Nucleic Acids Research, 2014
Genetic variation in UGT genes modify the associations of NSAIDs with risk of colorectal cancer: colon cancer family registry.
Scherer D et al.
Genes, Chromosomes & Cancer, 2014
Relevance of UDP-glucuronosyltransferase polymorphisms for drug dosing: A quantitative systematic review.
Stingl JC et al.
Pharmacology & Therapeutics, 2014
A signature of balancing selection in the region upstream to the human UGT2B4 gene and implications for breast cancer risk.
Sun C et al.
Human Genetics, 2011
Associations between polymorphisms in glucuronidation and sulfation enzymes and sex steroid concentrations in premenopausal women in the United States.
Yong M et al.
The Journal of Steroid Biochemistry and Molecular Biology, 2011
Associations between polymorphisms in glucuronidation and sulfation enzymes and mammographic breast density in premenopausal women in the United States.
Yong M et al.
Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2010
Limited influence of UGT1A1*28 and no effect of UGT2B7*2 polymorphisms on UGT1A1 or UGT2B7 activities and protein expression in human liver microsomes.
Peterkin VC et al.
British Journal of Clinical Pharmacology, 2007
Uridine diphosphoglucuronosyltransferase pharmacogenetics and cancer.
Nagar S et al.
Oncogene, 2006
The relationship between the pharmacology of antiepileptic drugs and human gene variation: an overview.
Ferraro TN et al.
Epilepsy & Behavior : E&b, 2005
Screening for deleterious nonsynonymous single-nucleotide polymorphisms in genes involved in steroid hormone metabolism and response.
Johnson MM et al.
Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2005
Single nucleotide polymorphisms and haplotype frequencies of UGT2B4 and UGT2B7 in a Japanese population.
Saeki M et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2004
UDP-glucuronosyltransferase and sulfotransferase polymorphisms, sex hormone concentrations, and tumor receptor status in breast cancer patients.
Sparks R et al.
Breast Cancer Research : Bcr, 2004
A pharmacogenetic study of uridine diphosphate-glucuronosyltransferase 2B7 in patients receiving morphine.
Sawyer MB et al.
Clinical Pharmacology and Therapeutics, 2003
Genetic variation of human UDP-glucuronosyltransferase: implications in disease and drug glucuronidation.
Burchell B
American Journal of Pharmacogenomics : Genomics-related Research in Drug Development and Clinical Practice, 2003
Prevalence of polymorphisms in the human UDP-glucuronosyltransferase 2B family: UGT2B4(D458E), UGT2B7(H268Y), and UGT2B15(D85Y).
Lampe JW et al.
Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2000
Single nucleotide polymorphisms: early diagnosis and risk assessment in genitourinary malignancy.
Kibel AS
Urologic Oncology, 0