Associated Papers
Development and Verification of Virtual Population Models for Predicting Drug Pharmacokinetics in Ethnic North American Populations.
Ezuruike U et al.
Cpt: Pharmacometrics & Systems Pharmacology, 2025
Contrastive sequence signatures between the both sides of a recombination spot reveal an adaptation at PPARD locus from standing variation for pleiotropy since out-of-Africa dispersal.
Shou W et al.
Bmc Genomics, 2025
Genetic variants in patients with multiple arterial aneurysms.
Körfer D et al.
Langenbeck's Archives of Surgery, 2024
ATR represents a therapeutic vulnerability in clear cell renal cell carcinoma.
Seidel P et al.
Jci Insight, 2022
Sensitization of Patient-Derived Colorectal Cancer Organoids to Photon and Proton Radiation by Targeting DNA Damage Response Mechanisms.
Pape K et al.
Cancers, 2022
Whole-exome sequencing identifies somatic mutations and intratumor heterogeneity in inflammatory breast cancer.
Luo R et al.
Npj Breast Cancer, 2021
Implication of UGT2B15 Genotype Polymorphism on Postoperative Anxiety Levels in Patients Receiving Lorazepam Premedication.
Mijderwijk H et al.
Anesthesia and Analgesia, 2016
Classical and Non-Classical Roles for Pre-Receptor Control of DHT Metabolism in Prostate Cancer Progression.
Zhang A et al.
Hormones & Cancer, 2016
Genetic polymorphisms of human UDP-glucuronosyltransferase (UGT) genes and cancer risk.
Hu DG et al.
Drug Metabolism Reviews, 2016
The eSNV-detect: a computational system to identify expressed single nucleotide variants from transcriptome sequencing data.
Tang X et al.
Nucleic Acids Research, 2014
Genetic variation in UGT genes modify the associations of NSAIDs with risk of colorectal cancer: colon cancer family registry.
Scherer D et al.
Genes, Chromosomes & Cancer, 2014
Relevance of UDP-glucuronosyltransferase polymorphisms for drug dosing: A quantitative systematic review.
Stingl JC et al.
Pharmacology & Therapeutics, 2014
Profiling serum bile acid glucuronides in humans: gender divergences, genetic determinants, and response to fenofibrate.
Trottier J et al.
Clinical Pharmacology and Therapeutics, 2013
A signature of balancing selection in the region upstream to the human UGT2B4 gene and implications for breast cancer risk.
Sun C et al.
Human Genetics, 2011
Associations between polymorphisms in glucuronidation and sulfation enzymes and sex steroid concentrations in premenopausal women in the United States.
Yong M et al.
The Journal of Steroid Biochemistry and Molecular Biology, 2011
Associations between polymorphisms in glucuronidation and sulfation enzymes and mammographic breast density in premenopausal women in the United States.
Yong M et al.
Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2010
Do single nucleotide polymorphisms in xenobiotic metabolizing genes determine breast cancer susceptibility and treatment outcomes?
Singh V et al.
Cancer Investigation, 2008
Limited influence of UGT1A1*28 and no effect of UGT2B7*2 polymorphisms on UGT1A1 or UGT2B7 activities and protein expression in human liver microsomes.
Peterkin VC et al.
British Journal of Clinical Pharmacology, 2007
Uridine diphosphoglucuronosyltransferase pharmacogenetics and cancer.
Nagar S et al.
Oncogene, 2006
The relationship between the pharmacology of antiepileptic drugs and human gene variation: an overview.
Ferraro TN et al.
Epilepsy & Behavior : E&b, 2005
Screening for deleterious nonsynonymous single-nucleotide polymorphisms in genes involved in steroid hormone metabolism and response.
Johnson MM et al.
Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2005
Single nucleotide polymorphisms and haplotype frequencies of UGT2B4 and UGT2B7 in a Japanese population.
Saeki M et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2004
UDP-glucuronosyltransferase and sulfotransferase polymorphisms, sex hormone concentrations, and tumor receptor status in breast cancer patients.
Sparks R et al.
Breast Cancer Research : Bcr, 2004
A pharmacogenetic study of uridine diphosphate-glucuronosyltransferase 2B7 in patients receiving morphine.
Sawyer MB et al.
Clinical Pharmacology and Therapeutics, 2003
Genetic variation of human UDP-glucuronosyltransferase: implications in disease and drug glucuronidation.
Burchell B
American Journal of Pharmacogenomics : Genomics-related Research in Drug Development and Clinical Practice, 2003
Prevalence of polymorphisms in the human UDP-glucuronosyltransferase 2B family: UGT2B4(D458E), UGT2B7(H268Y), and UGT2B15(D85Y).
Lampe JW et al.
Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2000
Single nucleotide polymorphisms: early diagnosis and risk assessment in genitourinary malignancy.
Kibel AS
Urologic Oncology, 0