Varaico: Literature-Extracted Genetic Variants

Gene:UGT2B4
Variant:p.H268Y
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UGT2B4

NM_021139.3:p.H268Y

Associated Papers

The letrozole phase 1 metabolite carbinol as a novel probe drug for UGT2B7.

Precht JC et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2013

Identification of human UGT isoforms responsible for glucuronidation of efavirenz and its three hydroxy metabolites.

Bae SK et al.

Xenobiotica; the Fate of Foreign Compounds in Biological Systems, 2011

Genetic polymorphism in metabolism and host defense enzymes: implications for human health risk assessment.

Ginsberg G et al.

Critical Reviews in Toxicology, 2010

Haplotype analysis of UDP-glucuronocyltransferase 2B7 gene (UGT2B7) polymorphisms in healthy Japanese subjects.

Saito K et al.

Clinical Biochemistry, 2006

Evaluation of 3'-azido-3'-deoxythymidine, morphine, and codeine as probe substrates for UDP-glucuronosyltransferase 2B7 (UGT2B7) in human liver microsomes: specificity and influence of the UGT2B7*2 polymorphism.

Court MH et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2003

A pharmacogenetic study of uridine diphosphate-glucuronosyltransferase 2B7 in patients receiving morphine.

Sawyer MB et al.

Clinical Pharmacology and Therapeutics, 2003

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."