Varaico: Literature-Extracted Genetic Variants

Gene:UGT2B7
Variant:p.R124R
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UGT2B7

NM_001074.4:p.R124R

Associated Papers

Low-dose lamotrigine co-administration decreases quetiapine plasma concentrations: Effect of UGT2B7-161C>T polymorphism in Japanese patients with depression.

Suzuki T et al.

International Journal of Clinical Pharmacology and Therapeutics, 2026

Impact of CYP2D6, MAOA, and UGT2B7 genetic variants on recurrence of Plasmodium Vivax in the Brazilian Amazon.

da Silva GS et al.

Scientific Reports, 2025

Tramadol-related fatalities: Metabolic ratios & SNPs/INDELs belonging to UGT1A8, UGT2B7, ABCC2, and SLC22A1.

Aly SM et al.

Forensic Science International. Genetics, 2025

CYP2B6 and ABCB1 genotypes predict methadone plasma exposure among patients on maintenance therapy against opioid addictions in Tanzania.

Mugusi S et al.

British Journal of Clinical Pharmacology, 2024

Characterization of ADME Gene Variation in Colombian Population by Exome Sequencing.

Silgado-Guzmán DF et al.

Frontiers in Pharmacology, 2022

35846994 (PubMed )
Supplement: Table1.xlsx › Hoja1

Estrogen profile- and pharmacogenetics-based lamotrigine dosing regimen optimization: Recommendations for pregnant women with epilepsy.

Wang ML et al.

Pharmacological Research, 2021

Evaluation of clinical and genetic factors in the population pharmacokinetics of carbamazepine.

Yip VLM et al.

British Journal of Clinical Pharmacology, 2021

Influence of SULT1A1*2 Polymorphism on Plasma Efavirenz Concentration in Thai HIV-1 Patients.

Chamnanphon M et al.

Pharmacogenomics and Personalized Medicine, 2021

Influence of genetic variants and antiepileptic drug co-treatment on lamotrigine plasma concentration in Mexican Mestizo patients with epilepsy.

Ortega-Vázquez A et al.

The Pharmacogenomics Journal, 2020

Pharmacogene Variation in Thai Plasmodium vivax Relapse Patients Treated with a Combination of Primaquine and Chloroquine.

Chamnanphon M et al.

Pharmacogenomics and Personalized Medicine, 2020

Effects of Comedication and Genetic Factors on the Population Pharmacokinetics of Lamotrigine: A Prospective Analysis in Chinese Patients With Epilepsy.

Wang ZZ et al.

Frontiers in Pharmacology, 2019

Interaction between ABCG2 421C>A polymorphism and valproate in their effects on steady-state disposition of lamotrigine in adults with epilepsy.

Klarica Domjanović I et al.

British Journal of Clinical Pharmacology, 2018

Influence of ABCC2, CYP2C8, and CYP2J2 Polymorphisms on Tacrolimus and Mycophenolate Sodium-Based Treatment in Brazilian Kidney Transplant Recipients.

Genvigir FDV et al.

Pharmacotherapy, 2017

Lack of genetic association between OCT1, ABCB1, and UGT2B7 variants and morphine pharmacokinetics.

Nielsen LM et al.

European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences, 2017

Allele and genotype frequencies of genes relevant to anti-epileptic drug therapy in Mexican-Mestizo healthy volunteers.

Fricke-Galindo I et al.

Pharmacogenomics, 2016

Pharmacokinetics of lamotrigine and its metabolite N-2-glucuronide: Influence of polymorphism of UDP-glucuronosyltransferases and drug transporters.

Milosheska D et al.

British Journal of Clinical Pharmacology, 2016

Effects of UGT2B7 Genetic Polymorphisms on Serum Concentrations of Valproic Acid in Chinese Children With Epilepsy Comedicated With Lamotrigine.

Wang Q et al.

Therapeutic Drug Monitoring, 2016

Rash and multiorgan dysfunction following lamotrigine: could genetic be involved?

Provenzani A et al.

International Journal of Clinical Pharmacy, 2015

An Expanded Analysis of Pharmacogenetics Determinants of Efavirenz Response that Includes 3'-UTR Single Nucleotide Polymorphisms among Black South African HIV/AIDS Patients.

Swart M et al.

Frontiers in Genetics, 2015

Influence of the UGT2B7 -161C>T polymorphism on the population pharmacokinetics of lamotrigine in Thai patients.

Singkham N et al.

European Journal of Clinical Pharmacology, 2013

Genetic factors associated with drug-resistance of epilepsy: relevance of stratification by patient age and aetiology of epilepsy.

Sánchez MB et al.

Seizure, 2010

Genetic variations in UDP-glucuronosyltransferase 2B7 gene (UGT2B7) in a Korean population.

Hwang MS et al.

Drug Metabolism and Pharmacokinetics, 2010

Single nucleotide polymorphism discovery and functional assessment of variation in the UDP-glucuronosyltransferase 2B7 gene.

Innocenti F et al.

Pharmacogenetics and Genomics, 2008

A pharmacogenetic study of uridine diphosphate-glucuronosyltransferase 2B7 in patients receiving morphine.

Sawyer MB et al.

Clinical Pharmacology and Therapeutics, 2003

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."