Varaico: Literature-Extracted Genetic Variants

Gene:UGT2B7
Variant:p.G241Splc
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UGT2B7

NM_001074.4:p.G241Splc

Associated Papers

Pharmacokinetics of free and total mycophenolic acid in paediatric and adult renal transplant recipients: Exploratory analysis of the effects of clinical factors and gene variants.

Liu Y et al.

Basic & Clinical Pharmacology & Toxicology, 2022

Influence of uridine diphosphate-glucuronosyltransferases (1A9) polymorphisms on mycophenolic acid pharmacokinetics in patients with renal transplant.

Ciftci HS et al.

Renal Failure, 2018

Pharmacogenetics of drug-metabolizing enzymes in US Hispanics.

Claudio-Campos K et al.

Drug Metabolism and Personalized Therapy, 2015

Associations of UDP-glucuronosyltransferases polymorphisms with mycophenolate mofetil pharmacokinetics in Chinese renal transplant patients.

Xie XC et al.

Acta Pharmacologica Sinica, 2015

Polymorphisms and haplotypes of the UDP-glucuronosyltransferase 2B7 gene promoter.

Hu DG et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2014

Worldwide variation in human drug-metabolism enzyme genes CYP2B6 and UGT2B7: implications for HIV/AIDS treatment.

Li J et al.

Pharmacogenomics, 2012

Chemokine (C-C motif) receptor 5 -2459 genotype in patients receiving highly active antiretroviral therapy: race-specific influence on virologic success.

Mehlotra RK et al.

The Journal of Infectious Diseases, 2011

Uridine 5'-diphospho-glucuronosyltransferase genetic polymorphisms and response to cancer chemotherapy.

Ramírez J et al.

Future Oncology (london, England), 2010

Interindividual variability in pharmacokinetics of generic nucleoside reverse transcriptase inhibitors in TB/HIV-coinfected Ghanaian patients: UGT2B7*1c is associated with faster zidovudine clearance and glucuronidation.

Kwara A et al.

Journal of Clinical Pharmacology, 2009

Functional significance of UDP-glucuronosyltransferase variants in the metabolism of active tamoxifen metabolites.

Blevins-Primeau AS et al.

Cancer Research, 2009

Single nucleotide polymorphism discovery and functional assessment of variation in the UDP-glucuronosyltransferase 2B7 gene.

Innocenti F et al.

Pharmacogenetics and Genomics, 2008

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."