Varaico: Literature-Extracted Genetic Variants

Gene:UGT2B7
Variant:p.T245T
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UGT2B7

NM_001074.4:p.T245T

Associated Papers

Tramadol-related fatalities: Metabolic ratios & SNPs/INDELs belonging to UGT1A8, UGT2B7, ABCC2, and SLC22A1.

Aly SM et al.

Forensic Science International. Genetics, 2025

Pharmacogenetics in Tuberculosis-HIV Coinfected Populations: A Systematic Review of Genetic Variants Influencing Antiretroviral and Anti-Tuberculosis Drug Response.

Hardi H et al.

Journal of Multidisciplinary Healthcare, 2025

Novel NARS2 variants in a patient with early-onset status epilepticus: case study and literature review.

Yang N et al.

Bmc Pediatrics, 2024

38310242 (PubMed )
Supplement: 12887_2024_4553_MOESM1_ESM.xlsx › trio.hg38.filter

Characterization of ADME Gene Variation in Colombian Population by Exome Sequencing.

Silgado-Guzmán DF et al.

Frontiers in Pharmacology, 2022

35846994 (PubMed )
Supplement: Table1.xlsx › Hoja1

Evaluation of clinical and genetic factors in the population pharmacokinetics of carbamazepine.

Yip VLM et al.

British Journal of Clinical Pharmacology, 2021

Influence of SULT1A1*2 Polymorphism on Plasma Efavirenz Concentration in Thai HIV-1 Patients.

Chamnanphon M et al.

Pharmacogenomics and Personalized Medicine, 2021

Meta-analysis of the effect of CYP2B6, CYP2A6, UGT2B7 and CAR polymorphisms on efavirenz plasma concentrations.

Ayuso P et al.

The Journal of Antimicrobial Chemotherapy, 2019

Human Genetic Variation and HIV/AIDS in Papua New Guinea: Time to Connect the Dots.

Mehlotra RK

Current Hiv/aids Reports, 2018

Identification and validation of the microRNA response elements in the 3'-untranslated region of the UDP glucuronosyltransferase (UGT) 2B7 and 2B15 genes by a functional genomics approach.

Papageorgiou I et al.

Biochemical Pharmacology, 2017

Pharmacogenetics of efavirenz discontinuation for reported central nervous system symptoms appears to differ by race.

Leger P et al.

Pharmacogenetics and Genomics, 2016

Effects of UGT2B7 Genetic Polymorphisms on Serum Concentrations of Valproic Acid in Chinese Children With Epilepsy Comedicated With Lamotrigine.

Wang Q et al.

Therapeutic Drug Monitoring, 2016

Pharmacogenetics of non-nucleoside reverse transcriptase inhibitors (NNRTIs) in resource-limited settings: Influence on antiretroviral therapy response and concomitant anti-tubercular, antimalarial and contraceptive treatments.

Russo G et al.

Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases, 2016

Perspectives on pharmacogenomics of antiretroviral medications and HIV-associated comorbidities.

Haas DW et al.

Current Opinion in Hiv and Aids, 2015

Secondary metabolism pathway polymorphisms and plasma efavirenz concentrations in HIV-infected adults with CYP2B6 slow metabolizer genotypes.

Haas DW et al.

The Journal of Antimicrobial Chemotherapy, 2014

Pharmacogenetic associations with plasma efavirenz concentrations and clinical correlates in a retrospective cohort of Ghanaian HIV-infected patients.

Sarfo FS et al.

The Journal of Antimicrobial Chemotherapy, 2014

Pharmacogenomics of antimicrobial agents.

Aung AK et al.

Pharmacogenomics, 2014

Correlates of efavirenz exposure in Chilean patients affected with human immunodeficiency virus reveals a novel association with a polymorphism in the constitutive androstane receptor.

Cortes CP et al.

Therapeutic Drug Monitoring, 2013

Worldwide variation in human drug-metabolism enzyme genes CYP2B6 and UGT2B7: implications for HIV/AIDS treatment.

Li J et al.

Pharmacogenomics, 2012

Chemokine (C-C motif) receptor 5 -2459 genotype in patients receiving highly active antiretroviral therapy: race-specific influence on virologic success.

Mehlotra RK et al.

The Journal of Infectious Diseases, 2011

Uridine 5'-diphospho-glucuronosyltransferase genetic polymorphisms and response to cancer chemotherapy.

Ramírez J et al.

Future Oncology (london, England), 2010

Interindividual variability in hepatic drug glucuronidation: studies into the role of age, sex, enzyme inducers, and genetic polymorphism using the human liver bank as a model system.

Court MH

Drug Metabolism Reviews, 2010

CYP2B6, CYP2A6 and UGT2B7 genetic polymorphisms are predictors of efavirenz mid-dose concentration in HIV-infected patients.

Kwara A et al.

Aids (london, England), 2009

Interindividual variability in pharmacokinetics of generic nucleoside reverse transcriptase inhibitors in TB/HIV-coinfected Ghanaian patients: UGT2B7*1c is associated with faster zidovudine clearance and glucuronidation.

Kwara A et al.

Journal of Clinical Pharmacology, 2009

Single nucleotide polymorphism discovery and functional assessment of variation in the UDP-glucuronosyltransferase 2B7 gene.

Innocenti F et al.

Pharmacogenetics and Genomics, 2008

Single nucleotide polymorphisms and haplotype frequencies of UGT2B4 and UGT2B7 in a Japanese population.

Saeki M et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2004

A pharmacogenetic study of uridine diphosphate-glucuronosyltransferase 2B7 in patients receiving morphine.

Sawyer MB et al.

Clinical Pharmacology and Therapeutics, 2003

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."