Varaico: Literature-Extracted Genetic Variants

Gene:UHRF1
Variant:p.D337A
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UHRF1

NM_001048201.3:p.D337A

Associated Papers

Structural basis for E3 ubiquitin ligase UHRF1 binding to nucleosome core particle and histone H3 ubiquitination.

Shikimachi R et al.

The Journal of Biological Chemistry, 2025

Molecular basis of hUHRF1 allosteric activation for synergistic histone modification binding by PI5P.

Mandal P et al.

Science Advances, 2022

Discovery and Mechanism of Small Molecule Inhibitors Selective for the Chromatin-Binding Domains of Oncogenic UHRF1.

Liu WH et al.

Biochemistry, 2022

Structure of the UHRF1 Tandem Tudor Domain Bound to a Methylated Non-histone Protein, LIG1, Reveals Rules for Binding and Regulation.

Kori S et al.

Structure (london, England : 1993), 2019

The PHD finger of human UHRF1 reveals a new subgroup of unmethylated histone H3 tail readers.

Lallous N et al.

Plos One, 2011

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."