Associated Papers
Uromodulin: Roles in Health and Disease.
Schaeffer C et al.
Annual Review of Physiology, 2021
Uromodulin: from physiology to rare and complex kidney disorders.
Devuyst O et al.
Nature Reviews. Nephrology, 2017
Early involvement of cellular stress and inflammatory signals in the pathogenesis of tubulointerstitial kidney disease due to UMOD mutations.
Trudu M et al.
Scientific Reports, 2017
A mouse model for inherited renal fibrosis associated with endoplasmic reticulum stress.
Piret SE et al.
Disease Models & Mechanisms, 2017
Rare ER protein misfolding-mistrafficking disorders: Therapeutic developments.
Hegde RN et al.
Tissue & Cell, 2017
Mitochondrial Dysregulation Secondary to Endoplasmic Reticulum Stress in Autosomal Dominant Tubulointerstitial Kidney Disease - UMOD (ADTKD-UMOD).
Kemter E et al.
Scientific Reports, 2017
No amelioration of uromodulin maturation and trafficking defect by sodium 4-phenylbutyrate in vivo: studies in mouse models of uromodulin-associated kidney disease.
Kemter E et al.
The Journal of Biological Chemistry, 2014
Uromodulin retention in thick ascending limb of Henle's loop affects SCD1 in neighboring proximal tubule: renal transcriptome studies in mouse models of uromodulin-associated kidney disease.
Horsch M et al.
Plos One, 2014
Type of uromodulin mutation and allelic status influence onset and severity of uromodulin-associated kidney disease in mice.
Kemter E et al.
Human Molecular Genetics, 2013
Uromodulin upregulates TRPV5 by impairing caveolin-mediated endocytosis.
Wolf MT et al.
Kidney International, 2013
Standardized, systemic phenotypic analysis of Umod(C93F) and Umod(A227T) mutant mice.
Kemter E et al.
Plos One, 2013
A transgenic mouse model for uromodulin-associated kidney diseases shows specific tubulo-interstitial damage, urinary concentrating defect and renal failure.
Bernascone I et al.
Human Molecular Genetics, 2010
Uromodulin is expressed in renal primary cilia and UMOD mutations result in decreased ciliary uromodulin expression.
Zaucke F et al.
Human Molecular Genetics, 2010
Uromodulin biology and pathophysiology--an update.
Vyletal P et al.
Kidney & Blood Pressure Research, 2010
Novel missense mutation of uromodulin in mice causes renal dysfunction with alterations in urea handling, energy, and bone metabolism.
Kemter E et al.
American Journal of Physiology. Renal Physiology, 2009
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