Associated Papers
Development of deaminase-free T-to-S base editor and C-to-G base editor by engineered human uracil DNA glycosylase.
Tong H et al.
Nature Communications, 2024
Unrepaired base excision repair intermediates in template DNA strands trigger replication fork collapse and PARP inhibitor sensitivity.
Serrano-Benitez A et al.
The Embo Journal, 2023
Uracil-DNA glycosylases-structural and functional perspectives on an essential family of DNA repair enzymes.
Schormann N et al.
Protein Science : a Publication of the Protein Society, 2014
Characterization of human cytomegalovirus uracil DNA glycosylase (UL114) and its interaction with polymerase processivity factor (UL44).
Ranneberg-Nilsen T et al.
Journal of Molecular Biology, 2008
Xenopus CENP-A assembly into chromatin requires base excision repair proteins.
Zeitlin SG et al.
Dna Repair, 2005
B cells from hyper-IgM patients carrying UNG mutations lack ability to remove uracil from ssDNA and have elevated genomic uracil.
Kavli B et al.
The Journal of Experimental Medicine, 2005
Mutational analysis of arginine 276 in the leucine-loop of human uracil-DNA glycosylase.
Chen CY et al.
The Journal of Biological Chemistry, 2004
A fission yeast homologue of the human uracil-DNA-glycosylase and their roles in causing DNA damage after overexpression.
Elder RT et al.
Biochemical and Biophysical Research Communications, 2003
Base excision repair initiation revealed by crystal structures and binding kinetics of human uracil-DNA glycosylase with DNA.
Parikh SS et al.
The Embo Journal, 1998
Crystal structure and mutational analysis of human uracil-DNA glycosylase: structural basis for specificity and catalysis.
Mol CD et al.
Cell, 1995
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