Varaico: Literature-Extracted Genetic Variants

Gene:USP12
Variant:p.C48S
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USP12

NM_182488.4:p.C48S

Associated Papers

Deubiquitinating Enzyme USP12 Regulates the Pro-Apoptosis Protein Bax.

Choi HS et al.

International Journal of Molecular Sciences, 2022

USP12 translocation maintains interferon antiviral efficacy by inhibiting CBP acetyltransferase activity.

Liu J et al.

Plos Pathogens, 2020

Deubiquitinase Usp12 functions noncatalytically to induce autophagy and confer neuroprotection in models of Huntington's disease.

Aron R et al.

Nature Communications, 2018

30266909 (PubMed )
Supplement: 41467_2018_5653_MOESM1_ESM.pdf

Allosteric Activation of Ubiquitin-Specific Proteases by β-Propeller Proteins UAF1 and WDR20.

Li H et al.

Molecular Cell, 2016

USP12 regulates cell cycle progression by involving c-Myc, cyclin D2 and BMI-1.

Tang LJ et al.

Gene, 2016

WD repeat protein WDR48 in complex with deubiquitinase USP12 suppresses Akt-dependent cell survival signaling by stabilizing PH domain leucine-rich repeat protein phosphatase 1 (PHLPP1).

Gangula NR et al.

The Journal of Biological Chemistry, 2013

UAF1 is a subunit of multiple deubiquitinating enzyme complexes.

Cohn MA et al.

The Journal of Biological Chemistry, 2009

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."