Varaico: Literature-Extracted Genetic Variants

Gene:USP15
Variant:p.L100I
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USP15

NM_001252078.2:p.L100I

Associated Papers

USP15 regulates radiation-induced DNA damage and intestinal injury through K48-linked deubiquitination and stabilisation of ATM.

Zhu R et al.

Molecular Medicine (cambridge, Mass.), 2024

K48-linked deubiquitination of VGLL4 by USP15 enhances the efficacy of tumor immunotherapy in triple-negative breast cancer.

Wang X et al.

Cancer Letters, 2024

The CRL3gigaxonin ubiquitin ligase-USP15 pathway governs the destruction of neurofilament proteins.

Park HM et al.

Proceedings of the National Academy of Sciences of the United States of America, 2023

Ubiquitination of RORγt at Lysine 446 Limits Th17 Differentiation by Controlling Coactivator Recruitment.

He Z et al.

Journal of Immunology (baltimore, Md. : 1950), 2016

USP4 Auto-Deubiquitylation Promotes Homologous Recombination.

Wijnhoven P et al.

Molecular Cell, 2015

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."