Varaico: Literature-Extracted Genetic Variants

Gene:USP2
Variant:p.C458S
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USP2

NM_004205.5:p.C458S

Associated Papers

Identification of ester-linked ubiquitylation sites during TLR7 signalling increases the number of inter-ubiquitin linkages from 8 to 12.

McCrory EH et al.

The Biochemical Journal, 2022

HOIL-1-catalysed, ester-linked ubiquitylation restricts IL-18 signaling in cytotoxic T cells but promotes TLR signalling in macrophages.

Petrova T et al.

The Febs Journal, 2021

The E3 ligase HOIL-1 catalyses ester bond formation between ubiquitin and components of the Myddosome in mammalian cells.

Kelsall IR et al.

Proceedings of the National Academy of Sciences of the United States of America, 2019

31209050 (PubMed )
Supplement: pnas.1905873116.sapp.pdf
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."