Associated Papers
USP25 Elevates SHLD2-Mediated DNA Double-Strand Break Repair and Regulates Chemoresponse in Cancer.
Li Y et al.
Advanced Science (weinheim, Baden-wurttemberg, Germany), 2024
Usp25-Erlin1/2 activity limits cholesterol flux to restrict virus infection.
Teo QW et al.
Developmental Cell, 2023
USP25 promotes pathological HIF-1-driven metabolic reprogramming and is a potential therapeutic target in pancreatic cancer.
Nelson JK et al.
Nature Communications, 2022
USP25 regulates Wnt signaling by controlling the stability of tankyrases.
Xu D et al.
Genes & Development, 2017
Tandem UIMs confer Lys48 ubiquitin chain substrate preference to deubiquitinase USP25.
Kawaguchi K et al.
Scientific Reports, 2017
Ubiquitin-specific protease 25 regulates TLR4-dependent innate immune responses through deubiquitination of the adaptor protein TRAF3.
Zhong B et al.
Science Signaling, 2013
Negative regulation of IL-17-mediated signaling and inflammation by the ubiquitin-specific protease USP25.
Zhong B et al.
Nature Immunology, 2012
The UBA-UIM domains of the USP25 regulate the enzyme ubiquitination state and modulate substrate recognition.
Denuc A et al.
Plos One, 2009
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