Varaico: Literature-Extracted Genetic Variants

Gene:USP30
Variant:p.A26D
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USP30

NM_032663.5:p.A26D

Associated Papers

Mechanism of activation and regulation of deubiquitinase activity in MINDY1 and MINDY2.

Abdul Rehman SA et al.

Molecular Cell, 2021

34529927 (PubMed )
Supplement: mmc1.pdf

Distinct USP25 and USP28 Oligomerization States Regulate Deubiquitinating Activity.

Gersch M et al.

Molecular Cell, 2019

30926242 (PubMed )
Supplement: mmc1.pdf

The structure of the deubiquitinase USP15 reveals a misaligned catalytic triad and an open ubiquitin-binding channel.

Ward SJ et al.

The Journal of Biological Chemistry, 2018

Mechanism and regulation of the Lys6-selective deubiquitinase USP30.

Gersch M et al.

Nature Structural & Molecular Biology, 2017

USP30 and parkin homeostatically regulate atypical ubiquitin chains on mitochondria.

Cunningham CN et al.

Nature Cell Biology, 2015

Quantitative proteomics reveal a feedforward mechanism for mitochondrial PARKIN translocation and ubiquitin chain synthesis.

Ordureau A et al.

Molecular Cell, 2014

The mitochondrial deubiquitinase USP30 opposes parkin-mediated mitophagy.

Bingol B et al.

Nature, 2014

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."