Associated Papers
USP30-mediated Deubiquitination of Hexokinase 2 controls the metabolic fate of glucose and tumor progression.
Haowei Z et al.
Cell Death & Disease, 2026
mTORC1-USP30-LEF1 Cascade Regulates Cancer Stemness and Malignant Progression Through Mitonuclear Crosstalk.
Li X et al.
Medcomm, 2025
Investigation of USP30 inhibition to enhance Parkin-mediated mitophagy: tools and approaches.
Tsefou E et al.
The Biochemical Journal, 2021
LRRK2 regulates endoplasmic reticulum-mitochondrial tethering through the PERK-mediated ubiquitination pathway.
Toyofuku T et al.
The Embo Journal, 2020
Deubiquitinating enzyme USP30 maintains basal peroxisome abundance by regulating pexophagy.
Riccio V et al.
The Journal of Cell Biology, 2019
Structural basis for specific cleavage of Lys6-linked polyubiquitin chains by USP30.
Sato Y et al.
Nature Structural & Molecular Biology, 2017
USP30 and parkin homeostatically regulate atypical ubiquitin chains on mitochondria.
Cunningham CN et al.
Nature Cell Biology, 2015
The mitochondrial deubiquitinase USP30 opposes parkin-mediated mitophagy.
Bingol B et al.
Nature, 2014
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