Varaico: Literature-Extracted Genetic Variants

Gene:USP35
Variant:p.R150R
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USP35

NM_020798.4:p.R150R

Associated Papers

The deubiquitylating enzyme USP35 restricts regulated cell death to promote survival of renal clear cell carcinoma.

Wang S et al.

Cell Death and Differentiation, 2023

USP35 dimer prevents its degradation by E3 ligase CHIP through auto-deubiquitinating activity.

Park J et al.

Cellular and Molecular Life Sciences : Cmls, 2023

USP35, regulated by estrogen and AKT, promotes breast tumorigenesis by stabilizing and enhancing transcriptional activity of estrogen receptor α.

Cao J et al.

Cell Death & Disease, 2021

Genome-wide suppressor screen identifies USP35/USP38 as therapeutic candidates for ciliopathies.

Tsai IC et al.

Jci Insight, 2019

USP35 regulates mitotic progression by modulating the stability of Aurora B.

Park J et al.

Nature Communications, 2018

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."