Associated Papers
The TDRD3-USP9X complex and MIB1 regulate TOP3B homeostasis and prevent deleterious TOP3B cleavage complexes.
Saha S et al.
Nature Communications, 2023
USP9X stabilizes BRCA1 and confers resistance to DNA-damaging agents in human cancer cells.
Lu Q et al.
Cancer Medicine, 2019
Inhibition of USP9X induces apoptosis in FLT3-ITD-positive AML cells cooperatively by inhibiting the mutant kinase through aggresomal translocation and inducing oxidative stress.
Akiyama H et al.
Cancer Letters, 2019
Crystal structure and activity-based labeling reveal the mechanisms for linkage-specific substrate recognition by deubiquitinase USP9X.
Paudel P et al.
Proceedings of the National Academy of Sciences of the United States of America, 2019
The deubiquitinase USP9X regulates FBW7 stability and suppresses colorectal cancer.
Khan OM et al.
The Journal of Clinical Investigation, 2018
The X-linked deubiquitinase USP9X is an integral component of centrosome.
Wang Q et al.
The Journal of Biological Chemistry, 2017
USP9X regulates centrosome duplication and promotes breast carcinogenesis.
Li X et al.
Nature Communications, 2017
The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma.
Pérez-Mancera PA et al.
Nature, 2012
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