Associated Papers
Disclosing Pathogenic Variant Effects on the Structural Dynamics of the VAPB MSP Domain Causing Familial ALS.
Bashar MA et al.
International Journal of Molecular Sciences, 2025
Pathogenic mechanisms of amyotrophic lateral sclerosis-linked VAPB P56S mutation in the degeneration of corticospinal motor neurons.
Yang X et al.
Ageing and Neurodegenerative Diseases, 2025
Secretion of endoplasmic reticulum protein VAPB/ALS8 requires topological inversion.
Kamemura K et al.
Nature Communications, 2024
Characterising the Genetic Landscape of Amyotrophic Lateral Sclerosis: A Catalogue and Assessment of Over 1,000 Published Genetic Variants.
McCann EP et al.
Journal of Neuromuscular Diseases, 2023
37638449 (PubMed )
Supplement: jnd-10-jnd230148-s001.xlsx › variant_list
VAP Proteins - From Organelle Tethers to Pathogenic Host Interactors and Their Role in Neuronal Disease.
Kors S et al.
Frontiers in Cell and Developmental Biology, 2022
Nearly 30 Years of Animal Models to Study Amyotrophic Lateral Sclerosis: A Historical Overview and Future Perspectives.
Bonifacino T et al.
International Journal of Molecular Sciences, 2021
Amyotrophic lateral sclerosis-associated Vap33 is required for maintaining neuronal dendrite morphology and organelle distribution in Drosophila.
Kamemura K et al.
Genes to Cells : Devoted to Molecular & Cellular Mechanisms, 2021
VAMP associated proteins are required for autophagic and lysosomal degradation by promoting a PtdIns4P-mediated endosomal pathway.
Mao D et al.
Autophagy, 2019
Neuronal overexpression of human VAPB slows motor impairment and neuromuscular denervation in a mouse model of ALS.
Kim JY et al.
Human Molecular Genetics, 2016
Investigating the contribution of VAPB/ALS8 loss of function in amyotrophic lateral sclerosis.
Kabashi E et al.
Human Molecular Genetics, 2013
Mutant VAPB: Culprit or Innocent Bystander of Amyotrophic Lateral Sclerosis?
Borgese N et al.
Contact (thousand Oaks (ventura County, Calif.)), 0
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