Varaico: Literature-Extracted Genetic Variants

Gene:VCP
Variant:p.Q603*
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VCP

NM_007126.5:p.Q603*

Associated Papers

Heterozygous mutations in valosin-containing protein (VCP) and resistance to VCP inhibitors.

Bastola P et al.

Scientific Reports, 2019

Structure and Function of the AAA+ ATPase p97, a Key Player in Protein Homeostasis.

Hänzelmann P et al.

Sub-cellular Biochemistry, 2019

Co-selected mutations in VCP: a novel mechanism of resistance to VCP inhibitors.

Bastola P et al.

Cell Death & Disease, 2018

Specific mutations in the D1-D2 linker region of VCP/p97 enhance ATPase activity and confer resistance to VCP inhibitors.

Bastola P et al.

Cell Death Discovery, 2017

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."