Varaico: Literature-Extracted Genetic Variants

Gene:VHL
Variant:p.R4S
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VHL

NM_000551.4:p.R4S

Associated Papers

A small-molecule VHL molecular glue degrader for cysteine dioxygenase 1.

Tutter A et al.

Nature Chemical Biology, 2025

Evaluation of Bridge Capture technology for mutation profiling in liquid biopsies of metastatic colorectal cancer patients.

Ganesan A et al.

Scientific Reports, 2025

Pan-Cancer Comparative and Integrative Analyses of Driver Alterations Using Japanese and International Genomic Databases.

Horie S et al.

Cancer Discovery, 2024

Incidental pathogenic germline alterations detected through liquid biopsy in patients with solid tumors: prevalence, clinical utility and implications.

Laguna JC et al.

British Journal of Cancer, 2024

Baseline mutational profiles of patients with carcinoma of unknown primary origin enrolled in the CUPISCO study.

Westphalen CB et al.

Esmo Open, 2023

37922692 (PubMed )
Supplement: mmc1.docx

Molecular profiling and feasibility using a comprehensive hybrid capture panel on a consecutive series of non-small-cell lung cancer patients from a single centre.

Mosteiro M et al.

Esmo Open, 2023

Targeting Ras with protein engineering.

Tomazini A et al.

Oncotarget, 2023

Clinicopathologic Characteristics and Outcomes for Patients With KRAS G12D-Mutant NSCLC.

Cooper AJ et al.

Jto Clinical and Research Reports, 2022

36118132 (PubMed )
Supplement: mmc2.docx

An In Vivo Inflammatory Loop Potentiates KRAS Blockade.

Arendt KAM et al.

Biomedicines, 2022

35327394 (PubMed )
Supplement: biomedicines-10-00592-s001.zip › biomedicines-1596404-supplementary.pdf

Clinical Implication of Concordant or Discordant Genomic Profiling between Primary and Matched Metastatic Tissues in Patients with Colorectal Cancer.

Choi JY et al.

Cancer Research and Treatment, 2020

Genomic profiling of primary histiocytic sarcoma reveals two molecular subgroups.

Egan C et al.

Haematologica, 2020

A KRAS wild type mutational status confers a survival advantage in pancreatic ductal adenocarcinoma.

Windon AL et al.

Journal of Gastrointestinal Oncology, 2018

Highly penetrant hereditary cancer syndromes.

Nagy R et al.

Oncogene, 2004

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."