Varaico: Literature-Extracted Genetic Variants

Gene:VHL
Variant:p.K159R
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VHL

NM_000551.4:p.K159R

Associated Papers

Quantitative insights into protein turnover and ubiquitination with HiBiT and NanoBRET.

Piechota M et al.

Methods in Enzymology, 2025

Lysine deserts and cullin-RING ligase receptors: Navigating untrodden paths in proteostasis.

Szulc NA et al.

Iscience, 2023

The von Hippel-Lindau Cullin-RING E3 ubiquitin ligase regulates APOBEC3 cytidine deaminases.

Scholtes GK et al.

Translational Research : the Journal of Laboratory and Clinical Medicine, 2021

Mdm2-mediated neddylation of pVHL blocks the induction of antiangiogenic factors.

Wolf ER et al.

Oncogene, 2020

Von Hippel-Lindau gene product directs cytokinesis: a new tumor suppressor function.

Sinha S et al.

Journal of Cell Science, 2011

Ubiquitin/SUMO modification regulates VHL protein stability and nucleocytoplasmic localization.

Cai Q et al.

Plos One, 2010

Hypoxia inactivates the VHL tumor suppressor through PIASy-mediated SUMO modification.

Cai Q et al.

Plos One, 2010

A molecular basis for stabilization of the von Hippel-Lindau (VHL) tumor suppressor protein by components of the VHL ubiquitin ligase.

Kamura T et al.

The Journal of Biological Chemistry, 2002

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."