Varaico: Literature-Extracted Genetic Variants

Gene:VKORC1
Variant:p.Y139S
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VKORC1

NM_024006.6:p.Y139S

Associated Papers

Vkorc1 gene polymorphisms confer resistance to anticoagulant rodenticide in Turkish rats.

Yiğit N et al.

Peerj, 2023

The screening for anticoagulant rodenticide gene VKORC1 polymorphism in the rat Rattus norvegicus, Rattus tanezumi and Rattus losea in Hong Kong.

Huang EYY et al.

Scientific Reports, 2022

The potential of VKORC1 polymorphisms in Mustelidae for evolving anticoagulant resistance through selection along the food chain.

Stöck M et al.

Plos One, 2019

31465484 (PubMed )
Supplement: pone.0221706.s004.xlsx › S4

Study of the efficiency of anticoagulant rodenticides to control Mus musculus domesticus introgressed with Mus spretus Vkorc1.

Goulois J et al.

Pest Management Science, 2017

Evidence of a target resistance to antivitamin K rodenticides in the roof rat Rattus rattus: identification and characterisation of a novel Y25F mutation in the Vkorc1 gene.

Goulois J et al.

Pest Management Science, 2016

Phylogeny of the Vitamin K 2,3-Epoxide Reductase (VKOR) Family and Evolutionary Relationship to the Disulfide Bond Formation Protein B (DsbB) Family.

Bevans CG et al.

Nutrients, 2015

Confirmation of warfarin resistance of naturally occurring VKORC1 variants by coexpression with coagulation factor IX and in silico protein modelling.

Müller E et al.

Bmc Genetics, 2014

Determination of the warfarin inhibition constant Ki for vitamin K 2,3-epoxide reductase complex subunit-1 (VKORC1) using an in vitro DTT-driven assay.

Bevans CG et al.

Biochimica Et Biophysica Acta, 2013

A new cell culture-based assay quantifies vitamin K 2,3-epoxide reductase complex subunit 1 function and reveals warfarin resistance phenotypes not shown by the dithiothreitol-driven VKOR assay.

Fregin A et al.

Journal of Thrombosis and Haemostasis : Jth, 2013

New insights into the catalytic mechanism of vitamin K epoxide reductase (VKORC1) - The catalytic properties of the major mutations of rVKORC1 explain the biological cost associated to mutations.

Matagrin B et al.

Febs Open Bio, 2013

Distribution of VKORC1 single nucleotide polymorphism in wild Rattus norvegicus in France.

Grandemange A et al.

Pest Management Science, 2010

Novel mutations in the VKORC1 gene of wild rats and mice--a response to 50 years of selection pressure by warfarin?

Rost S et al.

Bmc Genetics, 2009

The genetic basis of resistance to anticoagulants in rodents.

Pelz HJ et al.

Genetics, 2005

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."