Associated Papers
Rapid population expansion drives the widespread spread of a dominant anticoagulant-resistance Vkorc1 allele in Asian house rats (Rattus tanezumi) across China.
Sun T et al.
Pest Management Science, 2025
Vkorc1 gene polymorphisms confer resistance to anticoagulant rodenticide in Turkish rats.
Yiğit N et al.
Peerj, 2023
Investigation of anticoagulant rodenticide resistance induced by Vkorc1 mutations in rodents in Lebanon.
Rached A et al.
Scientific Reports, 2022
The screening for anticoagulant rodenticide gene VKORC1 polymorphism in the rat Rattus norvegicus, Rattus tanezumi and Rattus losea in Hong Kong.
Huang EYY et al.
Scientific Reports, 2022
Distribution of non-synonymous Vkorc1 mutations in roof rats (Rattus rattus) in France and in Spain - consequences for management.
Damin-Pernik M et al.
Pesticide Biochemistry and Physiology, 2022
VKORC1 mutations in rodent populations of a tropical city-state as an indicator of anticoagulant rodenticide resistance.
Chua C et al.
Scientific Reports, 2022
Establishment of the Variation of Vitamin K Status According to Vkorc1 Point Mutations Using Rat Models.
Debaux JV et al.
Nutrients, 2019
The potential of VKORC1 polymorphisms in Mustelidae for evolving anticoagulant resistance through selection along the food chain.
Stöck M et al.
Plos One, 2019
Elevated difenacoum metabolism is involved in the difenacoum-resistant phenotype observed in Berkshire rats homozygous for the L120Q mutation in the vitamin K epoxide reductase complex subunit 1 (Vkorc1) gene.
Boitet M et al.
Pest Management Science, 2018
Adaptative evolution of the Vkorc1 gene in Mus musculus domesticus is influenced by the selective pressure of anticoagulant rodenticides.
Goulois J et al.
Ecology and Evolution, 2017
Evidence of a target resistance to antivitamin K rodenticides in the roof rat Rattus rattus: identification and characterisation of a novel Y25F mutation in the Vkorc1 gene.
Goulois J et al.
Pest Management Science, 2016
Distribution of anticoagulant rodenticide resistance in Rattus norvegicus in the Netherlands according to Vkorc1 mutations.
Meerburg BG et al.
Pest Management Science, 2014
Confirmation of warfarin resistance of naturally occurring VKORC1 variants by coexpression with coagulation factor IX and in silico protein modelling.
Müller E et al.
Bmc Genetics, 2014
Determination of the warfarin inhibition constant Ki for vitamin K 2,3-epoxide reductase complex subunit-1 (VKORC1) using an in vitro DTT-driven assay.
Bevans CG et al.
Biochimica Et Biophysica Acta, 2013
New insights into the catalytic mechanism of vitamin K epoxide reductase (VKORC1) - The catalytic properties of the major mutations of rVKORC1 explain the biological cost associated to mutations.
Matagrin B et al.
Febs Open Bio, 2013
Vitamin K requirement and reproduction in bromadiolone-resistant Norway rats.
Jacob J et al.
Pest Management Science, 2012
Distribution of VKORC1 single nucleotide polymorphism in wild Rattus norvegicus in France.
Grandemange A et al.
Pest Management Science, 2010
Structure of a bacterial homologue of vitamin K epoxide reductase.
Li W et al.
Nature, 2010
Consequences of the Y139F Vkorc1 mutation on resistance to AVKs: in-vivo investigation in a 7th generation of congenic Y139F strain of rats.
Grandemange A et al.
Pharmacogenetics and Genomics, 2009
Novel mutations in the VKORC1 gene of wild rats and mice--a response to 50 years of selection pressure by warfarin?
Rost S et al.
Bmc Genetics, 2009
The genetic basis of resistance to anticoagulants in rodents.
Pelz HJ et al.
Genetics, 2005