Varaico: Literature-Extracted Genetic Variants

Gene:VKORC1
Variant:p.L120L
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VKORC1

NM_024006.6:p.L120L

Associated Papers

A New Cloud-Native Tool for Pharmacogenetic Analysis.

Yuan DY et al.

Genes, 2024

38540411 (PubMed )
Supplement: genes-15-00352-s001.zip › Pgxtools__a_new_cloud-native_tool_for_Pharmacogenetic_analysis-Supplemental-1-revised.pdf

Effect of donor GSTM3 rs7483 genetic variant on tacrolimus elimination in the early period after liver transplantation.

Zhang T et al.

Peerj, 2024

39465171 (PubMed )
Supplement: peerj-12-18360-s002.7z › drug-metabolizing_enzymes_and_transporter__DMET__microarray › markerlist.xlsx › markerlist.TXT

Characterization of ADME Gene Variation in Colombian Population by Exome Sequencing.

Silgado-Guzmán DF et al.

Frontiers in Pharmacology, 2022

35846994 (PubMed )
Supplement: Table1.xlsx › Hoja1

Comprehensive analysis of important pharmacogenes in Koreans using the DMET™ platform.

Kim B et al.

Translational and Clinical Pharmacology, 2021

Gene variants of coagulation related proteins that interact with SARS-CoV-2.

Holcomb D et al.

Plos Computational Biology, 2021

Potential impact on coagulopathy of gene variants of coagulation related proteins that interact with SARS-CoV-2.

Holcomb D et al.

Biorxiv : the Preprint Server for Biology, 2020

Feasibility of Integrating Panel-Based Pharmacogenomics Testing for Chemotherapy and Supportive Care in Patients With Colorectal Cancer.

Kasi PM et al.

Technology in Cancer Research & Treatment, 2019

31533552 (PubMed )
Supplement: OneOme_sample_comprehensive_report.pdf

Quantifying the effect of covariates on concentrations and effects of steady-state phenprocoumon using a population pharmacokinetic/pharmacodynamic model.

Abduljalil K et al.

Clinical Pharmacokinetics, 2013

Building individualized medicine: prevention of adverse reactions to warfarin therapy.

Krynetskiy E et al.

The Journal of Pharmacology and Experimental Therapeutics, 2007

Interethnic variability of warfarin maintenance requirement is explained by VKORC1 genotype in an Asian population.

Lee SC et al.

Clinical Pharmacology and Therapeutics, 2006

Mutations in VKORC1 cause warfarin resistance and multiple coagulation factor deficiency type 2.

Rost S et al.

Nature, 2004

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."