Associated Papers
Quantifying the effect of covariates on concentrations and effects of steady-state phenprocoumon using a population pharmacokinetic/pharmacodynamic model.
Abduljalil K et al.
Clinical Pharmacokinetics, 2013
Pharmacogenetics of oral anticoagulants: a basis for dose individualization.
Stehle S et al.
Clinical Pharmacokinetics, 2008
Building individualized medicine: prevention of adverse reactions to warfarin therapy.
Krynetskiy E et al.
The Journal of Pharmacology and Experimental Therapeutics, 2007
Different contributions of polymorphisms in VKORC1 and CYP2C9 to intra- and inter-population differences in maintenance dose of warfarin in Japanese, Caucasians and African-Americans.
Takahashi H et al.
Pharmacogenetics and Genomics, 2006
A polymorphism in the VKORC1 gene is associated with an interindividual variability in the dose-anticoagulant effect of warfarin.
D'Andrea G et al.
Blood, 2005
Mutations in VKORC1 cause warfarin resistance and multiple coagulation factor deficiency type 2.
Rost S et al.
Nature, 2004
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