Varaico: Literature-Extracted Genetic Variants

Gene:VKORC1
Variant:p.D38A
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VKORC1

NM_024006.6:p.D38A

Associated Papers

Stabilization of warfarin-binding pocket of VKORC1 and VKORL1 by a peripheral region determines their different sensitivity to warfarin inhibition.

Shen G et al.

Journal of Thrombosis and Haemostasis : Jth, 2018

Influence of CYP2C9 and VKORC1 on patient response to warfarin: a systematic review and meta-analysis.

Jorgensen AL et al.

Plos One, 2012

Building individualized medicine: prevention of adverse reactions to warfarin therapy.

Krynetskiy E et al.

The Journal of Pharmacology and Experimental Therapeutics, 2007

VKORC1 gene variations are the major contributors of variation in warfarin dose in Japanese patients.

Obayashi K et al.

Clinical Pharmacology and Therapeutics, 2006

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."