Associated Papers
Pharmacogenomics in cardiac therapy: Personalizing treatment for heart health.
Naderi N et al.
Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie, 2025
Comprehensive review of thrombophilia: pathophysiology, prevalence, risk factors, and molecular diagnosis.
Altwayan R et al.
Transfusion Clinique Et Biologique : Journal De La Societe Francaise De Transfusion Sanguine, 2025
Case Report: Decoding genetic risks of vascular parkinsonism: a case series.
Shalash A et al.
Frontiers in Genetics, 2025
Pharmacogenomics and genetic ancestry in Colombia: a study on all variant drug annotations of PharmGKB.
Acosta-Monterrosa AA et al.
Frontiers in Pharmacology, 2025
A comprehensive Thai pharmacogenomics database (TPGxD-1): Phenotype prediction and variants identification in 942 whole-genome sequencing data.
John S et al.
Clinical and Translational Science, 2024
ACE Phenotyping in Human Blood and Tissues: Revelation of ACE Outliers and Sex Differences in ACE Sialylation.
Enyedi EE et al.
Biomedicines, 2024
A New Cloud-Native Tool for Pharmacogenetic Analysis.
Yuan DY et al.
Genes, 2024
Being precise with anticoagulation to reduce adverse drug reactions: are we there yet?
Cross B et al.
The Pharmacogenomics Journal, 2024
VKORC1 polymorphisms and complete resistance to vitamin K antagonists: About two cases.
Benyamna I et al.
Biomedicine, 2024
Pharmacogenomic profiling of the South Korean population: Insights and implications for personalized medicine.
Youn MS et al.
Frontiers in Pharmacology, 2024
A Case of Unexplained Warfarin Resistance: A Case Report and Literature Review.
Favaedi M et al.
The Journal of Tehran Heart Center, 2023
Targeted next-generation sequencing of genes involved in Warfarin Pharmacodynamics and pharmacokinetics pathways using the Saudi Warfarin Pharmacogenetic study (SWAP).
Ammari MA et al.
The Pharmacogenomics Journal, 2023
Z-flipon variants reveal the many roles of Z-DNA and Z-RNA in health and disease.
Umerenkov D et al.
Life Science Alliance, 2023
Missense VKOR mutants exhibit severe warfarin resistance but lack VKCFD via shifting to an aberrantly reduced state.
Li S et al.
Blood Advances, 2023
Genomic medicine in Africa: a need for molecular genetics and pharmacogenomics experts.
Oluwole OG et al.
Current Medical Research and Opinion, 2023
One Rare Warfarin Resistance Case and Possible Mechanism Exploration.
Zhao L et al.
Pharmacogenomics and Personalized Medicine, 2023
Long-read HiFi sequencing of NUDT15: Phased full-gene haplotyping and pharmacogenomic allele discovery.
Scott ER et al.
Human Mutation, 2022
Warfarin Dosing in Patients With CYP2C9*5 Variant Alleles.
Lindley KJ et al.
Clinical Pharmacology and Therapeutics, 2022
Cross-ethnic analysis of common gene variants in hemostasis show lopsided representation of global populations in genetic databases.
Osman A et al.
Bmc Medical Genomics, 2022
Identification of pharmacogenetic variants from large scale next generation sequencing data in the Saudi population.
Goljan E et al.
Plos One, 2022
Characterization of ADME Gene Variation in Colombian Population by Exome Sequencing.
Silgado-Guzmán DF et al.
Frontiers in Pharmacology, 2022
Profiling of warfarin pharmacokinetics-associated genetic variants: Black Africans portray unique genetic markers important for an African specific warfarin pharmacogenetics-dosing algorithm.
Ndadza A et al.
Journal of Thrombosis and Haemostasis : Jth, 2021
Pharmacogenetic determinants of warfarin in the Indian population.
Naushad SM et al.
Pharmacological Reports : Pr, 2021
A study of elective genome sequencing and pharmacogenetic testing in an unselected population.
Cochran M et al.
Molecular Genetics & Genomic Medicine, 2021
Warfarin dosing algorithms: A systematic review.
Asiimwe IG et al.
British Journal of Clinical Pharmacology, 2021
Gene variants of coagulation related proteins that interact with SARS-CoV-2.
Holcomb D et al.
Plos Computational Biology, 2021
Development and Analytical Validation of a 29 Gene Clinical Pharmacogenetic Genotyping Panel: Multi-Ethnic Allele and Copy Number Variant Detection.
Scott SA et al.
Clinical and Translational Science, 2021
Genetic Polymorphism Effect on Warfarin-Rifampin Interaction: A Case Report and Review of Literature.
Salem M et al.
Pharmacogenomics and Personalized Medicine, 2021
Potential impact on coagulopathy of gene variants of coagulation related proteins that interact with SARS-CoV-2.
Holcomb D et al.
Biorxiv : the Preprint Server for Biology, 2020
Multiplexed measurement of variant abundance and activity reveals VKOR topology, active site and human variant impact.
Chiasson MA et al.
Elife, 2020
Role of Genetic Variations in the Hepatic Handling of Drugs.
Marin JJG et al.
International Journal of Molecular Sciences, 2020
CYP2C9-mediated warfarin and milk thistle interaction.
Lash DB et al.
Journal of Clinical Pharmacy and Therapeutics, 2020
The effect of genetic and nongenetic factors on warfarin dose variability in Qatari population.
Bader L et al.
The Pharmacogenomics Journal, 2020
Genome-wide analyses disclose the distinctive HLA architecture and the pharmacogenetic landscape of the Somali population.
Ali AA et al.
Scientific Reports, 2020
Population study of thrombophilic markers and pharmacogenetic markers of warfarin prevalence in Bosnia and Herzegovina.
Ašić A et al.
Croatian Medical Journal, 2019
Genetic variant in the promoter region of microRNA‑137 reduces the warfarin maintenance dose in patients with atrial fibrillation.
Tian Z et al.
Molecular Medicine Reports, 2019
The Genetics of Warfarin Dose-Response Variability in Africans: An Expert Perspective on Past, Present, and Future.
Ndadza A et al.
Omics : a Journal of Integrative Biology, 2019
VKORC1 variants as significant predictors of warfarin dose in Emiratis.
Al-Mahayri ZN et al.
Pharmacogenomics and Personalized Medicine, 2019
Assessment of coding region variants in Kuwaiti population: implications for medical genetics and population genomics.
John SE et al.
Scientific Reports, 2018
Comprehensive overview of the pharmacogenetic diversity in Ashkenazi Jews.
Zhou Y et al.
Journal of Medical Genetics, 2018
Utilizing Whole-Exome Sequencing to Characterize the Phenotypic Variability of Sickle Cell Disease.
Alsultan A et al.
Genetic Testing and Molecular Biomarkers, 2018
Pharmacogenetic and clinical predictors of response to clopidogrel plus aspirin after acute coronary syndrome in Egyptians.
Fathy S et al.
Pharmacogenetics and Genomics, 2018
N-Acetyltransferase-2 (NAT2) phenotype is influenced by genotype-environment interaction in Ethiopians.
Aklillu E et al.
European Journal of Clinical Pharmacology, 2018
Influence of genetic and non-genetic factors on acenocoumarol maintenance dose requirement in a Tunisian population.
Ajmi M et al.
European Journal of Clinical Pharmacology, 2018
Frequency of Common VKORC1 Polymorphisms and Their Impact on Warfarin Dose Requirement in Pakistani Population.
Qayyum A et al.
Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/hemostasis, 2018
VKORC1-1639A allele influences warfarin maintenance dosage among Blacks receiving warfarin anticoagulation: a retrospective cohort study.
Mili FD et al.
Future Cardiology, 2018
Genetic variation in human drug-related genes.
Schärfe CPI et al.
Genome Medicine, 2017