Varaico: Literature-Extracted Genetic Variants

Gene:VPS29
Variant:p.V90D
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VPS29

NM_016226.5:p.V90D

Associated Papers

Mutation in VPS35 associated with Parkinson's disease impairs WASH complex association and inhibits autophagy.

Zavodszky E et al.

Nature Communications, 2014

Endosomal recruitment of the WASH complex: active sequences and mutations impairing interaction with the retromer.

Helfer E et al.

Biology of the Cell, 2013

Identification of a conserved motif required for Vps35p/Vps26p interaction and assembly of the retromer complex.

Gokool S et al.

The Biochemical Journal, 2007

Vps29 has a phosphoesterase fold that acts as a protein interaction scaffold for retromer assembly.

Collins BM et al.

Nature Structural & Molecular Biology, 2005

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."