Varaico: Literature-Extracted Genetic Variants

Gene:VPS35
Variant:p.L625P
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VPS35

NM_018206.6:p.L625P

Associated Papers

Stabilizing the retromer complex rescues synaptic dysfunction and endosomal trafficking deficits in an Alzheimer's disease mouse model.

Ramonet D et al.

Acta Neuropathologica Communications, 2025

Challenge accepted: uncovering the role of rare genetic variants in Alzheimer's disease.

Khani M et al.

Molecular Neurodegeneration, 2022

Beware of Misdelivery: Multifaceted Role of Retromer Transport in Neurodegenerative Diseases.

Yoshida S et al.

Frontiers in Aging Neuroscience, 2022

Molecular Mechanisms Underlying Synaptic and Axon Degeneration in Parkinson's Disease.

Gcwensa NZ et al.

Frontiers in Cellular Neuroscience, 2021

VPS35, the core component of the retromer complex, and Parkinson's disease.

Luo AD et al.

Ibrain, 2021

The Retromer Complex and Sorting Nexins in Neurodegenerative Diseases.

Zhang H et al.

Frontiers in Aging Neuroscience, 2018

The Retromer Supports AMPA Receptor Trafficking During LTP.

Temkin P et al.

Neuron, 2017

De novo deleterious genetic variations target a biological network centered on Aβ peptide in early-onset Alzheimer disease.

Rovelet-Lecrux A et al.

Molecular Psychiatry, 2015

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."