Associated Papers
Rsp5/NEDD4 and ESCRT regulate TDP-43 toxicity and turnover via an endolysosomal clearance mechanism.
Byrd A et al.
The Journal of Cell Biology, 2026
Unveiling the physiological impact of ESCRT-dependent autophagosome closure by targeting the VPS37A ubiquitin E2 variant-like domain.
Hamamoto K et al.
Cell Reports, 2024
PTPN23-dependent ESCRT machinery functions as a cell death checkpoint.
Song D et al.
Nature Communications, 2024
The V-ATPase complex component RNAseK is required for lysosomal hydrolase delivery and autophagosome degradation.
Makar AN et al.
Nature Communications, 2024
Human cytomegalovirus deploys molecular mimicry to recruit VPS4A to sites of virus assembly.
Butt BG et al.
Plos Pathogens, 2024
Termination of STING responses is mediated via ESCRT-dependent degradation.
Balka KR et al.
The Embo Journal, 2023
Lysosomal trafficking of the glucose transporter GLUT1 requires sequential regulation by TXNIP and ubiquitin.
Qualls-Histed SJ et al.
Iscience, 2023
ESCRT-dependent STING degradation inhibits steady-state and cGAMP-induced signalling.
Gentili M et al.
Nature Communications, 2023
A conserved ubiquitin- and ESCRT-dependent pathway internalizes human lysosomal membrane proteins for degradation.
Zhang W et al.
Plos Biology, 2021
The ESCRT-III molecules regulate the apical targeting of bile salt export pump.
Wu SH et al.
Journal of Biomedical Science, 2021
Synthetic Lethal Interaction between the ESCRT Paralog Enzymes VPS4A and VPS4B in Cancers Harboring Loss of Chromosome 18q or 16q.
Neggers JE et al.
Cell Reports, 2020
De Novo VPS4A Mutations Cause Multisystem Disease with Abnormal Neurodevelopment.
Rodger C et al.
American Journal of Human Genetics, 2020
Aβ accumulation causes MVB enlargement and is modelled by dominant negative VPS4A.
Willén K et al.
Molecular Neurodegeneration, 2017
Asymmetric ring structure of Vps4 required for ESCRT-III disassembly.
Caillat C et al.
Nature Communications, 2015
The LXR-IDOL axis defines a clathrin-, caveolae-, and dynamin-independent endocytic route for LDLR internalization and lysosomal degradation.
Sorrentino V et al.
Journal of Lipid Research, 2013
Essential role of hIST1 in cytokinesis.
Agromayor M et al.
Molecular Biology of the Cell, 2009
The YPLGVG sequence of the Nipah virus matrix protein is required for budding.
Patch JR et al.
Virology Journal, 2008
Structural and mechanistic studies of VPS4 proteins.
Scott A et al.
The Embo Journal, 2005
Characterization of prototype foamy virus gag late assembly domain motifs and their role in particle egress and infectivity.
Stange A et al.
Journal of Virology, 2005
CHMP1 functions as a member of a newly defined family of vesicle trafficking proteins.
Howard TL et al.
Journal of Cell Science, 2001