Associated Papers
Updated global prevalence and ethnic diversity of von Willebrand disease based on population genetics analysis.
Seidizadeh O et al.
Scientific Reports, 2026
Predicting the effects of single pathological mutations in hemophilia A and type 2N von Willebrand diseases using AlphaFold2-multimer and AlphaFold3.
Zhang Z et al.
The Journal of Pharmacology and Experimental Therapeutics, 2025
The effects of pathogenic and likely pathogenic variants for inherited hemostasis disorders in 140 214 UK Biobank participants.
Stefanucci L et al.
Blood, 2023
Population-based prevalence and mutational landscape of von Willebrand disease using large-scale genetic databases.
Seidizadeh O et al.
Npj Genomic Medicine, 2023
Structural insights into blood coagulation factor VIII: Procoagulant complexes, membrane binding, and antibody inhibition.
Childers KC et al.
Journal of Thrombosis and Haemostasis : Jth, 2022
A novel mouse model of type 2N VWD was developed by CRISPR/Cas9 gene editing and recapitulates human type 2N VWD.
Shi Q et al.
Blood Advances, 2022
Type 2N VWD: Conclusions from the Spanish PCM-EVW-ES project.
Pérez-Rodríguez A et al.
Haemophilia : the Official Journal of the World Federation of Hemophilia, 2021
D' domain region Arg782-Cys799 of von Willebrand factor contributes to factor VIII binding.
Przeradzka MA et al.
Haematologica, 2020
Molecular and clinical profile of type 2 von Willebrand disease in Iran: a thirteen-year experience.
Rassoulzadegan M et al.
International Journal of Hematology, 2020
Evaluation of clinical severity in patients with type 2N von Willebrand disease using microchip-based flow-chamber system.
Nakajima Y et al.
International Journal of Hematology, 2020
Importance of the Force Field Choice in Capturing Functionally Relevant Dynamics in the von Willebrand Factor.
Kuzmanic A et al.
The Journal of Physical Chemistry Letters, 2019
The von Willebrand factor D'D3 assembly and structural principles for factor VIII binding and concatemer biogenesis.
Dong X et al.
Blood, 2019
Type 2N von Willebrand disease: Characterization and diagnostic difficulties.
Casonato A et al.
Haemophilia : the Official Journal of the World Federation of Hemophilia, 2018
A common ancestor more than 10,000 years old for patients with R854Q-related type 2N von Willebrand's disease in Italy.
Casonato A et al.
Haematologica, 2013
von Willebrand factor: the complex molecular genetics of a multidomain and multifunctional protein.
Schneppenheim R et al.
Journal of Thrombosis and Haemostasis : Jth, 2011
Recessive von Willebrand disease type 2 Normandy: variable expression of mild hemophilia and VWD type 1.
Michiels JJ et al.
Acta Haematologica, 2009
von Willebrand disease update: diagnostic and treatment dilemmas.
Bolton-Maggs PH et al.
Haemophilia : the Official Journal of the World Federation of Hemophilia, 2008
Management of inherited von Willebrand disease in 2007.
Federici AB et al.
Annals of Medicine, 2007
Classification and characterization of hereditary types 2A, 2B, 2C, 2D, 2E, 2M, 2N, and 2U (unclassifiable) von Willebrand disease.
Michiels JJ et al.
Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/hemostasis, 2006
New insight into the molecular basis of hemophilia A.
Oldenburg J et al.
International Journal of Hematology, 2006
Type 2N von Willebrand disease mutations in Brazilian individuals.
Simon D et al.
Haemophilia : the Official Journal of the World Federation of Hemophilia, 2004
Recombinant expression of mutations causing von Willebrand disease type Normandy: characterization of a combined defect of factor VIII binding and multimerization.
Schneppenheim R et al.
Thrombosis and Haemostasis, 2004
The molecular biology of von Willebrand disease.
Keeney S et al.
Clinical and Laboratory Haematology, 2001