Varaico: Literature-Extracted Genetic Variants

Gene:WAS
Variant:p.G12V
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WAS

NM_000377.3:p.G12V

Associated Papers

WASP Restricts Active Rac to Maintain Cells' Front-Rear Polarization.

Amato C et al.

Current Biology : Cb, 2019

X-linked thrombocytopenia causing mutations in WASP (L46P and A47D) impair T cell chemotaxis.

Jain N et al.

Journal of Biomedical Science, 2014

Stimulation of actin polymerization by vacuoles via Cdc42p-dependent signaling.

Isgandarova S et al.

The Journal of Biological Chemistry, 2007

Rac1 and Rac3 isoform activation is involved in the invasive and metastatic phenotype of human breast cancer cells.

Baugher PJ et al.

Breast Cancer Research : Bcr, 2005

Ras superfamily monomeric G proteins in carcinoma cell motility.

Oxford G et al.

Cancer Letters, 2003

Wiskott-Aldrich syndrome protein induces actin clustering without direct binding to Cdc42.

Kato M et al.

The Journal of Biological Chemistry, 1999

Novel Cdc42-binding proteins Gic1 and Gic2 control cell polarity in yeast.

Brown JL et al.

Genes & Development, 1997

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."