Varaico: Literature-Extracted Genetic Variants

Gene:WDR5
Variant:p.D107A
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WDR5

NM_017588.3:p.D107A

Associated Papers

Structural characterization of endogenous microprotein EMBOW reveals an alternative MRT motif for WDR5-interacting site recognition.

Yang Y et al.

The Febs Journal, 2026

The NTE domain of PTENα/β promotes cancer progression by interacting with WDR5 via its SSSRRSS motif.

Huang X et al.

Cell Death & Disease, 2024

An Embryonic Stem Cell-Specific NuRD Complex Functions through Interaction with WDR5.

Ee LS et al.

Stem Cell Reports, 2017

Essential role of lncRNA binding for WDR5 maintenance of active chromatin and embryonic stem cell pluripotency.

Yang YW et al.

Elife, 2014

WDR5 interacts with mixed lineage leukemia (MLL) protein via the histone H3-binding pocket.

Song JJ et al.

The Journal of Biological Chemistry, 2008

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."