Varaico: Literature-Extracted Genetic Variants

Gene:WDR5
Variant:p.Y191F
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WDR5

NM_017588.3:p.Y191F

Associated Papers

Crystal structures of Kif2A complexed with WDR5 reveal the structural plasticity of WIN-S7 sites.

Yang Y et al.

Acta Biochimica Et Biophysica Sinica, 2025

A SET-domain-independent role of WRAD complex in cell-cycle regulatory function of mixed lineage leukemia.

Ali A et al.

Nucleic Acids Research, 2014

The role of WDR5 in silencing human fetal globin gene expression.

Xu Z et al.

Haematologica, 2012

A conserved arginine-containing motif crucial for the assembly and enzymatic activity of the mixed lineage leukemia protein-1 core complex.

Patel A et al.

The Journal of Biological Chemistry, 2008

How chromatin-binding modules interpret histone modifications: lessons from professional pocket pickers.

Taverna SD et al.

Nature Structural & Molecular Biology, 2007

Regulation of MLL1 H3K4 methyltransferase activity by its core components.

Dou Y et al.

Nature Structural & Molecular Biology, 2006

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."