Varaico: Literature-Extracted Genetic Variants

Gene:WLS
Variant:p.S412S
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WLS

NM_024911.7:p.S412S

Associated Papers

Systematic Review of Pharmacogenetics of ABC and SLC Transporter Genes in Acute Myeloid Leukemia.

Megías-Vericat JE et al.

Pharmaceutics, 2022

Overexpression of P-glycoprotein and MRP-1 are pharmacogenomic biomarkers to determine steroid resistant phenotype in childhood idiopathic nephrotic syndrome.

Prasad N et al.

The Pharmacogenomics Journal, 2021

Pharmacogenetic Foundations of Therapeutic Efficacy and Adverse Events of Statins.

Arrigoni E et al.

International Journal of Molecular Sciences, 2017

Causes and Consequences of Variability in Drug Transporter Activity in Pediatric Drug Therapy.

Rodieux F et al.

Journal of Clinical Pharmacology, 2016

Efflux pump ABCB1 single nucleotide polymorphisms and dose reductions in patients with metastatic renal cell carcinoma treated with sunitinib.

Beuselinck B et al.

Acta Oncologica (stockholm, Sweden), 2014

MDR1 polymorphisms associated with risk and survival in diffuse large B-cell lymphoma.

Hu LL et al.

Leukemia & Lymphoma, 2013

Variation and evolution of the ABC transporter genes ABCB1, ABCC1, ABCG2, ABCG5 and ABCG8: implication for pharmacogenetics and disease.

Silverton L et al.

Drug Metabolism and Drug Interactions, 2011

Placental P-glycoprotein and breast cancer resistance protein: influence of polymorphisms on fetal drug exposure and physiology.

Hutson JR et al.

Placenta, 2010

Pharmacogenetics as a tool for optimising drug therapy in solid-organ transplantation.

Ng FL et al.

Expert Opinion on Pharmacotherapy, 2007

Role of pharmacogenetics of ATP-binding cassette transporters in the pharmacokinetics of drugs.

Cascorbi I

Pharmacology & Therapeutics, 2006

Genetic polymorphisms of drug transporters: pharmacokinetic and pharmacodynamic consequences in pharmacotherapy.

Ieiri I et al.

Expert Opinion on Drug Metabolism & Toxicology, 2006

MDR1 haplotype frequencies in Japanese and Caucasian, and in Japanese patients with colorectal cancer and esophageal cancer.

Komoto C et al.

Drug Metabolism and Pharmacokinetics, 2006

Genetic predictors of the clinical response to opioid analgesics: clinical utility and future perspectives.

Lötsch J et al.

Clinical Pharmacokinetics, 2004

MDR1 genotype-related pharmacokinetics and pharmacodynamics.

Sakaeda T et al.

Biological & Pharmaceutical Bulletin, 2002

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."