Varaico: Literature-Extracted Genetic Variants

Gene:WNK2
Variant:p.G12V
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WNK2

NM_006648.4:p.G12V

Associated Papers

Discovery of a novel ERK inhibitor with activity in models of acquired resistance to BRAF and MEK inhibitors.

Morris EJ et al.

Cancer Discovery, 2013

23614898 (PubMed )
Supplement: 21598290cd130070-sup-supplementary_figures_-_pdf_file_1385k.pdf

Protein kinase WNK2 inhibits cell proliferation by negatively modulating the activation of MEK1/ERK1/2.

Moniz S et al.

Oncogene, 2007

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."