Varaico: Literature-Extracted Genetic Variants

Gene:WNK3
Variant:p.L297F
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WNK3

NM_020922.5:p.L297F

Associated Papers

WNK3 and WNK4 exhibit opposite sensitivity with respect to cell volume and intracellular chloride concentration.

Pacheco-Alvarez D et al.

American Journal of Physiology. Cell Physiology, 2020

Physiological Processes Modulated by the Chloride-Sensitive WNK-SPAK/OSR1 Kinase Signaling Pathway and the Cation-Coupled Chloride Cotransporters.

Murillo-de-Ozores AR et al.

Frontiers in Physiology, 2020

Unique chloride-sensing properties of WNK4 permit the distal nephron to modulate potassium homeostasis.

Terker AS et al.

Kidney International, 2016

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."