Associated Papers
WNK3 and WNK4 exhibit opposite sensitivity with respect to cell volume and intracellular chloride concentration.
Pacheco-Alvarez D et al.
American Journal of Physiology. Cell Physiology, 2020
With no lysine L-WNK1 isoforms are negative regulators of the K+-Cl- cotransporters.
Mercado A et al.
American Journal of Physiology. Cell Physiology, 2016
Similar effects of all WNK3 variants on SLC12 cotransporters.
Cruz-Rangel S et al.
American Journal of Physiology. Cell Physiology, 2011
WNK2 kinase is a novel regulator of essential neuronal cation-chloride cotransporters.
Rinehart J et al.
The Journal of Biological Chemistry, 2011
The WNKs: atypical protein kinases with pleiotropic actions.
McCormick JA et al.
Physiological Reviews, 2011
Renal and brain isoforms of WNK3 have opposite effects on NCCT expression.
Glover M et al.
Journal of the American Society of Nephrology : Jasn, 2009
Thick ascending limb: the Na(+):K (+):2Cl (-) co-transporter, NKCC2, and the calcium-sensing receptor, CaSR.
Gamba G et al.
Pflugers Archiv : European Journal of Physiology, 2009
WNK3 and WNK4 amino-terminal domain defines their effect on the renal Na+-Cl- cotransporter.
San-Cristobal P et al.
American Journal of Physiology. Renal Physiology, 2008
Regulation of NKCC2 by a chloride-sensing mechanism involving the WNK3 and SPAK kinases.
Ponce-Coria J et al.
Proceedings of the National Academy of Sciences of the United States of America, 2008
The thiazide-sensitive Na-Cl cotransporter is regulated by a WNK kinase signaling complex.
Yang CL et al.
The Journal of Clinical Investigation, 2007
WNK4 kinase is a negative regulator of K+-Cl- cotransporters.
Garzón-Muvdi T et al.
American Journal of Physiology. Renal Physiology, 2007
[Clinical significance of thiazide-sensitive Na-Cl cotransporter gene by mutational analysis].
Yasujima M
Rinsho Byori. the Japanese Journal of Clinical Pathology, 2007
WNK3, a kinase related to genes mutated in hereditary hypertension with hyperkalaemia, regulates the K+ channel ROMK1 (Kir1.1).
Leng Q et al.
The Journal of Physiology, 2006