Varaico: Literature-Extracted Genetic Variants

Gene:WRN
Variant:p.D82A
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WRN

NM_000553.6:p.D82A

Associated Papers

Sequence-specific processing of telomeric 3' overhangs by the Werner syndrome protein exonuclease activity.

Li B et al.

Aging, 2009

Modeling Werner Syndrome in Drosophila melanogaster: hyper-recombination in flies lacking WRN-like exonuclease.

Cox LS et al.

Annals of the New York Academy of Sciences, 2007

Werner syndrome: molecular insights into the relationships between defective DNA metabolism, genomic instability, cancer and aging.

Orren DK

Frontiers in Bioscience : a Journal and Virtual Library, 2006

RecQ helicases: suppressors of tumorigenesis and premature aging.

Bachrati CZ et al.

The Biochemical Journal, 2003

Requirements for the nucleolytic processing of DNA ends by the Werner syndrome protein-Ku70/80 complex.

Li B et al.

The Journal of Biological Chemistry, 2001

Characterization of the human and mouse WRN 3'-->5' exonuclease.

Huang S et al.

Nucleic Acids Research, 2000

A frameshift mutation in human MC4R is associated with a dominant form of obesity.

Vaisse C et al.

Nature Genetics, 1998

The premature ageing syndrome protein, WRN, is a 3'-->5' exonuclease.

Huang S et al.

Nature Genetics, 1998

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."