Varaico: Literature-Extracted Genetic Variants

Gene:WWP1
Variant:p.P297H
Back to variants list

WWP1

NM_007013.4:p.P297H

Associated Papers

CYYR1 promotes the degradation of the E3 ubiquitin ligase WWP1 and is associated with favorable prognosis in breast cancer.

Perron T et al.

The Journal of Biological Chemistry, 2024

The Penta-EF-Hand ALG-2 Protein Interacts with the Cytosolic Domain of the SOCE Regulator SARAF and Interferes with Ubiquitination.

Zhang W et al.

International Journal of Molecular Sciences, 2020

Reactivation of PTEN tumor suppressor for cancer treatment through inhibition of a MYC-WWP1 inhibitory pathway.

Lee YR et al.

Science (new York, N.y.), 2019

Functional Characterization of a WWP1/Tiul1 Tumor-derived Mutant Reveals a Paradigm of Its Constitutive Activation in Human Cancer.

Courivaud T et al.

The Journal of Biological Chemistry, 2015

Ezrin ubiquitylation by the E3 ubiquitin ligase, WWP1, and consequent regulation of hepatocyte growth factor receptor activity.

Zaarour RF et al.

Plos One, 2012

The E3 ubiquitin ligase WWP1 regulates ΔNp63-dependent transcription through Lys63 linkages.

Peschiaroli A et al.

Biochemical and Biophysical Research Communications, 2010

WW domain containing E3 ubiquitin protein ligase 1 targets the full-length ErbB4 for ubiquitin-mediated degradation in breast cancer.

Li Y et al.

Oncogene, 2009

WW domain-containing E3 ubiquitin protein ligase 1 targets p63 transcription factor for ubiquitin-mediated proteasomal degradation and regulates apoptosis.

Li Y et al.

Cell Death and Differentiation, 2008

The Nedd4-like family of E3 ubiquitin ligases and cancer.

Chen C et al.

Cancer Metastasis Reviews, 2007

Select a paper to view details
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."