Varaico: Literature-Extracted Genetic Variants

Gene:XAF1
Variant:p.L33R
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XAF1

NM_017523.5:p.L33R

Associated Papers

Epigenetic silencing of XAF1 in high-grade gliomas is associated with IDH1 status and improved clinical outcome.

Reich TR et al.

Oncotarget, 2017

XAF1 directs apoptotic switch of p53 signaling through activation of HIPK2 and ZNF313.

Lee MG et al.

Proceedings of the National Academy of Sciences of the United States of America, 2014

ZNF313 is a novel cell cycle activator with an E3 ligase activity inhibiting cellular senescence by destabilizing p21(WAF1.).

Han J et al.

Cell Death and Differentiation, 2013

XAF1 directs glioma response to temozolomide through apoptotic transition of autophagy by activation of ATM-AMPK signaling.

Lee MG et al.

Neuro-oncology Advances, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."