Varaico: Literature-Extracted Genetic Variants

Gene:XIAP
Variant:p.C213G
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XIAP

NM_001167.4:p.C213G

Associated Papers

Structure shows that the BIR2 domain of E3 ligase XIAP binds across the RIPK2 kinase dimer interface.

Lethier M et al.

Life Science Alliance, 2023

Disruption of XIAP-RIP2 Association Blocks NOD2-Mediated Inflammatory Signaling.

Goncharov T et al.

Molecular Cell, 2018

Copper-binding properties of the BIR2 and BIR3 domains of the X-linked inhibitor of apoptosis protein.

Liang Y et al.

Journal of Inorganic Biochemistry, 2014

Structural and biophysical characterization of XIAP BIR3 G306E mutant: insights in protein dynamics and application for fragment-based drug design.

Moore CD et al.

Chemical Biology & Drug Design, 2009

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."